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Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal memb...

Marques, Carolina; Oliveira, C. Suellen F.; Alves, Sara; Chaves, S. R.; Coutinho, O. P.; Côrte-Real, Manuela; Preto, Ana

Colorectal carcinoma (CRC) is one of the most common causes of cancer-related mortality. Short-chain fatty acids secreted by dietary propionibacteria from the intestine, such as acetate, induce apoptosis in CRC cells and may therefore be relevant in CRC prevention and therapy. We previously reported that acetic acid-induced apoptosis in Saccharomyces cerevisiae cells involves partial vacuole permeabilization an...


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