110 documents found, page 1 of 11

Bipolar disorder diagnostic stability: a Portuguese multicentric study

Human Papillomavirus Type Distribution in Cervical Intraepithelial Neoplasia Gr...

OBJECTIVE: Cervical cancer is the third most frequent cancer in women, worldwide and etiologically associated with infection by human papillomavirus (HPV). Following the results of the first epidemiologic population-based CLEOPATRE study in Portugal, it was important to understand the HPV type-specific distribution in women with cervical intraepithelial neoplasia (CIN) grades 2 and 3 and invasive cervical cance...

Risk factors for human papilomavirus infection among women in Portugal: the CLE...

OBJECTIVE: Human papillomavirus (HPV) is responsible for a range of diseases, including cervical cancer. The primary objectives of the CLEOPATRE Portugal study were to estimate the overall and age-stratified prevalence of cervical HPV infection and to assess HPV prevalence and type-specific distribution by cytological results among women aged 18 to 64 years, who reside in mainland Portugal. MATERIALS AND METHOD...

Influence of normal mammary epithelium on breast cancer progression: the protec...

AIMS AND BACKGROUND: The microenvironment has a well recognized role in breast cancer progression. Despite different theories, the mechanism of early pregnancy protection in mammary carcinogenesis is unknown. Since pregnancy is responsible for mammary gland differentiation, we tested the hypothesis that differentiated mammary epithelial cells may inhibit breast cancer progression. In other words, the protective...

Sequential adjuvant chemotherapy and radiotherapy in endometrial cancer--result...

INTRODUCTION: Endometrial cancer patients with high grade tumours, deep myometrial invasion or advanced stage disease have a poor prognosis. Randomised studies have demonstrated the prevention of loco-regional relapses with radiotherapy (RT) with no effect on overall survival (OS). The possible additive effect of chemotherapy (CT) remains unclear. Two randomised clinical trials (NSGO-EC-9501/EORTC-55991 and MaN...

Tumor de células de Leydig do ovário: caso clínico

Leydig cell tumours account for 0.1% of all ovarian tumours and are a type of steroid cell tumour. According to the World Health Organisation they are classified in the group of sex cord stromal tumours. The clinical presentation is usually a hyperandrogenic state with signs of virilisation, but occasionally patients may exhibit a hyperestrogenic state. The tumour has a benign behaviour, with an excellent progn...

Effect of simvastatin on metastasis-specific mouse mammary carcinoma 4T1 cells ...

Bibliometria do Cancro em Portugal: 1997 a 2006

Introdução: Analisou-se a produção científica das instituições portuguesas na área específica da Oncologia, durante um período de 10 anos, 1997 a 2006. Verificou-se a contribuição dos autores nacionais na produção científica internacional, o que permitiu julgar e quantificar a importância de autores, departamentos, instituições e investigações científicas. Material e Métodos: Usando a versão de 2006 da Web of S...

Aspiração eco-guiada de lesões quísticas do ovário

Introduction and Objective: In the last two decades the increased accuracy of ultrasonography has allowed simple ovarian cysts to be reliably identified. As clinical data suggest that simple cystic lesions rarely become malignant, surgical treatment of these cysts may therefore represent overtreatment. Our study aimed to evaluate the results of ultrasound (US) guided aspiration of cystic ovarian lesions perform...

Breast cancer patients with micrometastases in sentinel lymph nodes: difference...