8 documents found, page 1 of 1
Circulating micrornas correlate with multiple myeloma and skeletal osteolytic l...
Moura, SR; Abreu, H; Cunha, C; Ribeiro-Machado, C; Oliveira, CM; Barbosa, MA; Marques, H; Almeida, MIMultiple myeloma (MM) is the second most frequent hematological disease and can cause skeletal osteolytic lesions. This study aims to evaluate the expression of circulating microRNAs (miR-NAs) in MM patients and to correlate those levels with clinicopathological features, including bone lesions. A panel of miRNAs associated with MM onset and progression, or with bone remodeling, was analyzed in the plasma of 82...
Urinary incontinence in women who practice recreational exercise: A cross-secti...
Silva, MF; Costa, RP; Oliveira, CM; Moreira, SIntroduction: Urinary incontinence affects up to one third of women in Portugal. Exercise can be a precipitating/aggravating factor but also protective, if appropriate. The aim of this study was to determine the prevalence of urinary incontinence in women who practice recreational exercise, to assess its relationship with the type of exercise and other coexisting risk factors, and assess whether the topic is ad...
Regional drinking water composition effects on hip fracture risk: A spatial ana...
Oliveira, CM; Teixeira, H; Alves, SM; Pina, MFGeographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged =50 years, diagnosed with HF caused by low/moderate energy traumas. ...
Childhood cancer: Incidence and spatial patterns in the city of Campinas, Brazi...
Friestino, J; Mendonça, D; Oliveira, P; Oliveira, CM; Filho, DThis article analyzes cancer incidence and spatial patterns in children and adolescents (0-19 years of age) residing in the city of Campinas in Southeastern Brazil who were diagnosed from 1996-2005. Cancers were classified according to the Third International Classification of Childhood Cancer (ICCC-3) Groups. The four most common groups were studied: leukemias, lymphomas, and central nervous system and soft ti...
The interactions between municipal socioeconomic status and age on hip fracture...
Oliveira, CM; Economou, T; Bailey, T; Mendonça, D; Pina, MFSummary: Age modifies the effect of area-level socioeconomic status (SES) in the risk of fragility hip fractures (HF). For older individuals, the risk of HF increases as SES increases. For younger individuals, risk of HF increases as SES decreases. Our study may help decision-makers to better direct the implementation of political decisions.; Introduction: The effect of socioeconomic status (SES) on hip fractur...
Finding and tracing human MSC in 3D microenvironments with the photoconvertible...
Caires, HR; Gomez-Lazaro, M; Oliveira, CM; Gomes, D; Mateus, DD; Oliveira, C; Barrias, CC; Barbosa, MA; Almeida, CRMesenchymal Stem/Stromal Cells (MSC) are a promising cell type for cell-based therapies - from tissue regeneration to treatment of autoimmune diseases - due to their capacity to migrate to damaged tissues, to differentiate in different lineages and to their immunomodulatory and paracrine properties. Here, a simple and reliable imaging technique was developed to study MSC dynamical behavior in natural and bioeng...
Age-period-cohort effects in the incidence of hip fractures: political and econ...
Alves, SM; Castiglione, D; Oliveira, CM; de Sousa, B; Pina, MFSummary: An age–period cohort model was fitted to analyse time effects on hip fracture incidence rates by sex (Portugal, 2000–2008). Rates increased exponentially with age (age effect). Incidence rates decreased after 2004 for women and were random for men (period effect). New but comprehensive fluctuations in risk were coincident with major political/economic changes (cohort effect). Introduction: Healthcare i...
Ocular Risk Factors for Exudative AMD: A Novel Semiautomated Grading System
Marques, JP; Costa, M; Melo, P; Oliveira, CM; Pires, I; Cachulo, ML; Figueira, J; Silva, RPurpose. To evaluate the contribution of the ocular risk factors in the conversion of the fellow eye of patients with unilateral exudative AMD, using a novel semiautomated grading system. Materials and Methods. Single-center, retrospective study including 89 consecutive patients with unilateral exudative AMD and ≥3 years of followup. Baseline color fundus photographs were graded using an innovative grading soft...