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Transformações químicas do (+)-10β,14-diol-allo-aromadendrano, isolado de dugue...
Lima, Dênis Pires de; Beatriz, Adilson; Ramos, Alexandre Ayoroa; Siqueira, João Máximo de; Oliveira, Celso Corrêa de; Marques, Maria RitaThe sesquiterpene (+)-allo-aromadendrane-10β-14-diol 1 was the lead compound to the preparation of several derivatives in order to test their biological activity against A. salina, C. sphaerospermum, E. coli and S. aureus. In this way the monoalcohols (+)-viridiflorol 4, 9 and 11 were synthesized from 1 together with the acetal 6, the ketal 7, and the ketone 8. The oxirane 3 and nitrile 5 were also prepared usi...
Date: 2011
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Origin: Oasisbr