Eucalyptus essential oils and extracts are widely recognized for their antimicrobial, antioxidant, insecticidal, anti-inflammatory, and aromatizing properties, making them highly valuable across pharmaceuticals, cosmetics, and textiles. For the design of biomedical textiles, cotton is favored for its mechanical strength, porosity, and biodegradability, but its vulnerability to microbial action limits its applic...
Bioactive textiles have emerged as multifunctional materials to actively interact with the human skin and its microbiome. By embedding natural or synthetic bioactive compounds, such as chitosan, essential oils, plant extracts, and metallic nanoparticles, these materials aim to prevent and target infections, modulate inflammation, and promote skin homeostasis. Given the critical role of the skin microbiome in ma...
Background: Malassezia spp. are lipid-dependent yeasts that are an important part of the normal skin mycobiome in humans and other warm-blooded animals. Although generally harmless, they can, under certain conditions, contribute to skin disorders, with Malassezia furfur (M. furfur) being the main species linked to invasive infections. Current treatment mainly relies on topical or systemic antifungals, which, de...
Background: Oral diseases affect over three billion peopleand are among the most commonly observed infections worldwide. Recent studies have shown that controlling the ecology of the oralome is more effective in reducing the risk of caries than the complete removal of both harmful and beneficial microorganisms. This work aimed to develop a strategy for preventing dysbiosis in the oral cavity by applying a postb...
The development of antimicrobial textiles has gained increasing attention due to rising concerns regarding infection control and material safety, Conventional antimicrobial textiles often depend on synthetic agents or metal-based compounds, which may promote environmental and biocompatibility concerns. Hybrid strategies combining nanotechnology with bioactive compounds (BCs) derived from agri-food by-products h...
The agricultural and food sectors generate substantial amounts of by-products that are usually discarded as waste. However, agri-food by-products, rich in many bioactive compounds (BCs), can find several applications while promoting sustainability. Acorn shell (AS) and red grape pomace (RGP) stand out as valuable sources of BCs. To be used in human skin, the biological properties of these by-products need to be...
This study investigates the incorporation of natural plant extracts, particularly eucalyptus and hop, into knitted fabrics to develop antimicrobial textiles. The antibacterial activity of the functionalized fabrics was evaluated against two pathogenic bacteria (Staphylococcus aureus and Escherichia coli) and one common skin commensal (Staphylococcus epidermidis). Biocompatibility with human skin cells was asses...
Background: Candida spp. are commensal yeasts that inhabit the skin and mucous membranes and are the leading cause of invasive fungal infections. Mucocutaneous candidiasis is a common condition, often treated with azoles and polyenes, which may cause side effects and foster resistance. Essential oils (EOs), natural compounds with antimicrobial activity, present a promising alternative due to their multi-target ...
Introduction: Candida spp. are commensal yeasts that inhabit the skin and mucous membranes and are the leading cause of invasive fungal infections (Lopes et al. 2024). Mucocutaneous candidiasis is a common condition, often treated with azoles and polyenes, which can cause side effects and promote resistance (Tortorano et al., 2021). Essential oils (EOs), natural compounds with antimicrobial activity, present a ...
The skin microbiome, composed of bacteria like Staphylococcus spp. and Cutibacterium acnes and fungi such as Candida spp. and Malasseziaspp., plays a key role in skin health (Byrd et al., 2018). Dysbiosis, or microbial imbalance, is linked to conditions like acne and dermatitis (Egert etal., 2017). While conventional treatments, such as anti-inflammatory drugs and antimicrobials, can help, they may disrupt the ...