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Exploring risk factors linked to canine lymphoma: a case-control study

Pinello, K; Leite-Martins, L; Gregório, H; Oliveira, F; Kimura, KC; Dagli, MLZ; de Matos, A; Niza-Ribeiro, J

Environmental factors, largely influenced by human behavior, account for approximately 80 % of malignant tumors. Risk factors associated with non-Hodgkin's lymphoma (NHL) have been identified in various countries among both humans and domestic animals. This study aimed to investigate potential risk factors for NHL in dogs residing in the district of Porto, Portugal. A comprehensive survey comprising 70 question...


Relatório científico da Expedição Oceano Azul - Cascais | Mafra | Sintra

Cabral, H; Afonso, CML; Almada, F; Almeida, S; Alonso, H; Andrade, J; Anjos, M; Batista, M; Bentes, L; Carvalho, AC; Celestino, S; Coelho, PD; Coxey, M

A zona marítima dos concelhos de Cascais, Mafra e Sintra tem sido pouco estudada, não obstante situar-se frente a grandes centros urbanos e ser alvo de diversos usos e atividades humanas. Algumas das suas características geográficas e dos seus elementos notáveis ao nível dos fundos marinhos acrescem o seu interesse científico e patrimonial. Com o objectivo de ampliar o conhecimento científico sobre a biodiversi...


Setting Performance Indicators for Coastal Marine Protected Areas: An Expert-Ba...

Cardoso-Andrade, M; Queiroga, H; Rangel, M; Sousa, I; Belackova, A; Bentes, L; Oliveira, F; Monteiro, P; Sales Henriques, N; Afonso, CML; Silva, AF

Marine Protected Areas (MPAs) require effective indicators to assess their performance, in compliance with the goals of relevant national and international commitments. Achieving and prioritizing shortlists of multidisciplinary indicators demands a significant effort from specialists to depict the multiple conservation and socioeconomic interests, and the large complexity of natural systems. The present paper d...


Catálogo da exposição “Áreas Marinhas Protegidas da Costa Sudoeste”

Quintella, BR; Horta e Costa, B; Pinto, B; Silva, AF; Sousa, I; Antunes, M; Coelho, P; Costa, JL; Almeida, PR; Marques, JP; Teodoro, PF; Costa, A

Catálogo da exposição “Áreas Marinhas Protegidas da Costa Sudoeste”.


Primary Anti-Phospholipid Antibody Syndrome: Real-World Defining Features of Re...

Moraes-Fontes, MF; Pedro, F; Campos, MM; Fernandes, M; Yavuz, S; Oliveira, F; Panarra, A

Objective: We aimed to identify features that allow differentiation of primary antiphospholipid syndrome (PAPS) patients that suffer recurrent thrombotic events (RTE) despite anticoagulation, from the other diagnosed PAPS patients. Methods: This was an exploratory study of anticoagulated PAPS patients attending an Autoimmune Diseases Unit (1998-2018). From 2016, anti-phospholipid antibodies and lupus anticoagul...


Áreas Marinhas Protegidas da Costa Sudoeste

Quintella, BR; Horta e Costa, B; Costa, JL; Silva, AF; Sousa, I; Antunes, M; Coelho, P; Pinto, B; Costa, T; Almeida, P. R.; Marques, JP; Teodoro, PF

Áreas Marinhas Protegidas da Costa Sudoeste.


Fighting Staphylococcus epidermidis Biofilm-Associated Infections: Can Iron Be ...

Oliveira, F; Rohde, H; Vilanova, M; Cerca, N

Staphylococcus epidermidis is one of the most important commensal microorganisms of human skin and mucosae. However, this bacterial species is also the cause of severe infections in immunocompromised patients, specially associated with the utilization of indwelling medical devices, that often serve as a scaffold for biofilm formation. S. epidermidis strains are often multidrug resistant and its association with...


Protective efficacy in a hamster model of a multivalent vaccine for human visce...

Fernández, L; Solana, JC; Sánchez, C; Jiménez, MÁ; Requena, JM; Coler, R; Reed, SG; Valenzuela, JG; Kamhawi, S; Oliveira, F; Fichera, E; Glueck, R

Visceral leishmaniasis (VL) is the most severe clinical form of leishmaniasis, fatal if un-treated. Vaccination is the most cost-effective approach to disease control; however, to date, no vaccines against human VL have been made available. This work examines the efficacy of a novel vaccine consisting of the Leishmania membrane protein KMP11, LEISH-F3+ (a recombinant fusion protein, composed of epitopes of the ...


Siderophore-Mediated Iron Acquisition Plays a Critical Role in Biofilm Formatio...

Oliveira, F; Lima, T; Correia, A; Silva, AM; Soares, C; Morais, S; Weißelberg, S; Vilanova, M; Rohde, H; Cerca, N

Iron acquisition through siderophores, a class of small, potent iron-chelating organic molecules, is a widely spread strategy among pathogens to survive in the iron-restricted environment found in the host. Although these molecules have been implicated in the pathogenesis of several species, there is currently no comprehensive study addressing siderophore production in Staphylococcus epidermidis. Staphylococcus...


Engineering a vector-based pan-Leishmania vaccine for humans: proof of principle

Cecílio, P; Oristian, J; Meneses, C; Serafim, TD; Valenzuela, JG; Cordeiro-da-Silva, A; Oliveira, F

Leishmaniasis is a spectrum of diseases transmitted by sand fly vectors that deposit Leishmania spp. parasites in the host skin during blood feeding. Currently, available treatment options are limited, associated with high toxicity and emerging resistance. Even though a vaccine for human leishmaniasis is considered an achievable goal, to date we still do not have one available, a consequence (amongst other fact...


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