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Mixed infection by Histoplasma capsulatum isolates with different mating types ...

Damasceno, Lisandra Serra; Vite-Garín, Tania; Ramírez, José Antonio; Rodríguez-Arellanes, Gabriela; Almeida, Marcos Abreu de; Muniz, Mauro de Medeiros

Mixed infection by Histoplasma capsulatum isolates with different mating types, in AIDS‑patients are described in this study. Morphological, mating type-specific PCR assay and multilocus sequencing type analysis of H. capsulatum isolates recovered from two Brazilian AIDS‑patients were performed. Five H. capsulatum isolates were recovered at different times from the two patients. Three isolates were obtained fro...

Date: 2019   |   Origin: Oasisbr

Mixed infection by Histoplasma capsulatum isolates with different mating types ...

Damasceno, Lisandra Serra; Vite-Garín, Tania; Ramírez, José Antonio; Rodríguez-Arellanes, Gabriela; Almeida, Marcos Abreu de; Muniz, Mauro de Medeiros

Mixed infection by Histoplasma capsulatum isolates with different mating types, in AIDS-patients are described in this study. Morphological, mating type-specific PCR assay and multilocus sequencing type analysis of H. capsulatum isolates recovered from two Brazilian AIDS-patients were performed. Five H. capsulatum isolates were recovered at different times from the two patients. Three isolates were obtained fro...

Date: 2019   |   Origin: Oasisbr

Antiretroviral drugs saquinavir and ritonavir reduce inhibitory concentration v...

Brilhante, Raimunda Sâmia Nogueira; Caetano, Érica Pacheco; Riello, Giovanna Barbosa Riello; Guedes, Glaucia Morgana de Melo

Recent studies have shown that some drugs that are not routinely used to treat fungalinfections have antifungal activity, such as protease inhibitor antiretroviral drugs. This studyinvestigated the in vitro susceptibility of Histoplasma capsulatum var. capsulatum to saquinavirand ritonavir, and its combination with the antifungal itraconazole. The susceptibility assaywas performed according to Clinical and Labo...

Date: 2016   |   Origin: Oasisbr

Screening of antimicrobial metabolite yeast isolates derived biome Ceará agains...

Andrade Neto, João Batista de; Silva, Cecília R. da; Nascimento, Francisca Bruna Stefany Aires do; Sampaio, Letícia Serpa; Silva, Anderson R. da

Antimicrobials benefited the history of medicine by revolutionizing the treatment of infectious diseases. However, its consequent and continuous use has led to the emergence of microorganisms which once were considered safe, but have become feared as potentially lethal pathogens (Bowler et al., 2012). Staphylococcus aureus infections are highlighted for being a major cause of systemic infections, and for being ...

Date: 2016   |   Origin: Oasisbr

Effects of piperonal nitro derivatives on candida species : antifungal activity...

Andrade Neto, João Batista de; Silva, Cecília Rocha da; Campos, Rosana de Sousa; Nascimento, Francisca Bruna Stefany Aires do; Freitas, Daniel Domingues

Recently, there has been a significant increase in invasive fungal infections, the treatment of which is limited to a quite small number of antifungal drugs. Natural products represent an important source of antifungal agents, mainly because of their natural coexistence with fungi present in each biome. Derivatives or semi-synthetic products can be used to optimize the pharmacological profile of natural product...

Date: 2016   |   Origin: Oasisbr

Ciprofloxacin shows synergism with classical antifungals against Histoplasma ca...

Caetano, Erica Pacheco; Brilhante, Raimunda Sâmia Nogueira; Sidrim, José Júlio Costa; Cordeiro, Rossana de Aguiar; Camargo, Zoilo Pires de

This study evaluated the in vitro interaction between ciprofloxacin (CIP) and classical antifungals against Histoplasma capsulatum var. capsulatum in mycelial (n = 16) and yeast-like forms (n = 9) and Coccidioides posadasii in mycelial form (n = 16). This research was conducted through broth microdilution and macrodilution, according to Clinical Laboratory Standards Institute. Inocula were prepared to obtain fr...

Date: 2013   |   Origin: Oasisbr

Coccidioidomycosis in armadillo hunters from the state of Ceará, Brazil

Brillhante, Raimunda Sâmia Nogueira; Moreira Filho, Renato Evando; Rocha, Marcos Fábio Gadelha; Castelo-Branco, Débora de Souza Collares Maia

Coccidioidomycosis is a systemic mycosis with a variable clinical presentation. Misdiagnosis of coccidioidomycosis as bacterial pneumopathy leads to inappropriate prescription of antibiotics and delayed diagnosis. This report describes an outbreak among armadillo hunters in northeastern Brazil in which an initial diagnosis of bacterial pneumonia was later confirmed as coccidioidomycosis caused by Coccidioides p...

Date: 2013   |   Origin: Oasisbr

Perfil clínico-epidemiológico de infecções respiratórias agudas causadas por ad...

Mesquita, Jacó Ricarte Lima de

Adenoviruses (Ad) are important etiological agents of acute respiratory infections (ARI) in children, particularly between six months and five years old. This was a retrospective study, whose objectives were: to perform clinical and epidemiologic profile of adenoviral respiratory infections in children attended in Hospital Infantil Albert Sabin, in the city of Fortaleza, from January 2001 to December 2006; to o...

Date: 2012   |   Origin: Oasisbr

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