3 documents found, page 1 of 1
Potential involvement of oxidative stress in induction of neurodegenerative dis...
Oliveira, George Laylson da Silva; Oliveira, Francisco Rodrigo de Asevedo Mendes de; Freitas, Rivelilson Mendes deSeveral studies have shown that oxidative damage to various org ans of a given organism is involved in causing various diseases, and in this context, the brain is hig hly vulnerable to oxidative stress because of its high metabolic rate, low capacity of cell regeneration, small amounts of enzymatic and non- enzymatic antioxidants. Oxidative stress is caused by an imbala nce in cell redox state, in which there i...
Evaluation of antioxidant capacity of the aqueous extract of Cynara scolymus L....
Oliveira, George Laylson da Silva; Oliveira, Francisco Rodrigo de Asevedo Mendes de; Alencar, Marcus Vinícius Oliveira Barros deThe present study evaluated the antioxidant capacity of the aqueous extract of the leaves of Cynara scolymus on Saccharomyces cerevisiae strains, proficient and deficient in antioxidant defenses, and by in vitro methods with 1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2'-azinobis-3-ethylbenzothiazoline-6- sulfonic acid (ABTS•+), inhibition of hydrogen peroxide, lipid peroxidation, formation of nitric oxide, and re...
Prospecção tecnológica : utilização de alcaloides no tratamento da doença de al...
Oliveira, Francisco Rodrigo de Asevedo Mendes de; Oliveira, George Laylson da Silva; Oliveira, Johanssy da SilvaAlzheimer's disease (AD) is a neurological disorder that affects more people around the world. Currently, natural compounds derived from plants such as alkaloids, may be a promising alternative, effective and with fewer side effects for the development of drugs for AD. The aim of this study was to perform a technological forecasting alkaloids for the treatment of AD, analyzing the amount of records deposits pat...