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Antischistosomal activity of the terpene nerolidol

Silva, Marcos P.N.; Oliveira, George L.S.; Carvalho, Rusbene B.F. de; Sousa, Damião P. de; Freitas, Rivelilson M.; Pinto, Pedro L.S.; Moraes, Josué de

Schistosomiasis is a neglected tropical disease that affects hundreds of millions of people worldwide. Since the treatment of this disease currently relies on a single drug, praziquantel, new and safe schistosomicidal agents are urgently required. Nerolidol, a sesquiterpene present in the essential oils of several plants, is found in many foods and was approved by the U.S. Food and Drug Administration. In this ...

Date: 2014   |   Origin: Oasisbr
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