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An overview on immunogenic cell death in cancer biology and therapy

Rodrigues, Mosar Corrêa; Morais, José Athayde Vasconcelos; Ganassin, Rayane; Oliveira, Giulia Rosa Tavares; Costa, Fabiana Chagas

Immunogenic cell death (ICD) is a modality of regulated cell death that is sufficient to promote an adaptive immune response against antigens of the dying cell in an immunocompetent host. An important characteristic of ICD is the release and exposure of damage-associated molecular patterns, which are potent endogenous immune adjuvants. As the induction of ICD can be achieved with conventional cytotoxic agents, ...

Date: 2022   |   Origin: Oasisbr

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