3 documents found, page 1 of 1
The impact of NOS3 gene polymorphism on papillary thyroid cancer susceptibility...
Cerqueira, Adara Rodrigues Damasceno; Fratelli, Caroline Ferreira; Duarte, Ligia Canongia de Abreu Cardoso; Pereira, Alexandre Sampaio RodriguesThyroid cancer is the most common endocrine cancer in the world. Noting that the NOS3 gene polymorphism interferes with nitric oxide production, this study aims to identify and analyze the NOS3 gene polymorphism in the intron 4 region in patients with papillary thyroid cancer. A case-control study was conducted with 31 papillary thyroid cancer patients of both genders who underwent thyroidectomy and treatment w...
The role of the NIS (SLC5A5) gene in Papillary thyroid cancer : a systematic re...
Morais, Rafael Martins de; Barra Sobrinho, Alaor; Silva, Calliandra Maria de Souza; Oliveira, Jamila Reis de; Silva, Izabel Cristina Rodrigues daPapillary thyroid cancer (PTC) is the most common thyroid malignancy. Genetic and epigenetic alterations play a decisive role in the onset of several human neoplasms. Mutations and polymorphisms are two frequent genetic alterations. Located on chromosome 19 (19p13.11), the NIS SLC5A5 (solute carrier family 5 member 5) gene encodes a highly specialized and efficient 80–90 kDa transmembrane glycoprotein that medi...
Immunolocalization of HLA-DR and metallothionein on amalgam tattoos
Leite, Camila Megale de Almeida; Botelho, Amanda S.; Oliveira, Jamila Reis de; Cardoso, Sérgio Vitorino; Loyola, Adriano Mota; Gomez, Ricardo SantiagoDespite studies concerning toxic reactions related to amalgam components in the literature, few studies have been devoted to evaluate local noxious effects of amalgam tattoos (AT) on biological tissues. In addition, little is known about activation of inflammatory cells by mucosa-implanted amalgam debris. Tissue reaction to AT depends on the particle size. Human leukocyte antigen DR (HLA-DR) is an activation ma...