3 documents found, page 1 of 1
Produtos naturais aplicados a doenças negligenciadas : prospecção tecnológica
Oliveira, Johanssy da Silva; Machado, Keylla da Conceição; Freitas, Rivelilson Mendes deThe use of natural products is an innovative alternative to the research and development of new targeted drugs for the treatment of neglected tropical diseases. These are a group of diseases that have high prevalence rates in emerging countries where sanitary conditions and poor health are Revista GEINTEC – ISSN: 2237-0722. São Cristóvão/SE – 2014. Vol. 4/n.2/ p.729-734 730 D.O.I.: 10.7198/S2237-072220140002000...
Avaliação da toxicidade aguda do epóxilimoneno em camundongos adultos
Almeida, Antonia Amanda Cardoso de; Carvalho, Rusbene Bruno Fonseca de; Sousa, Damião Pergentino de; Souza, Geane Felix de; Oliveira, Johanssy da SilvaIntroduction: the biodiversity of global flora provides important molecules for the treatment and prevention of various human diseases, but most often their toxicities are not evaluated. Objective: evaluate the toxicity of monoterpenoid limonene epoxidein mice treated acutely with repeated doses (25, 50 and 75 mg/kg) orally on hematological and biochemical parameters. Methods: forty mice divided infour groups (...
Prospecção tecnológica : utilização de alcaloides no tratamento da doença de al...
Oliveira, Francisco Rodrigo de Asevedo Mendes de; Oliveira, George Laylson da Silva; Oliveira, Johanssy da SilvaAlzheimer's disease (AD) is a neurological disorder that affects more people around the world. Currently, natural compounds derived from plants such as alkaloids, may be a promising alternative, effective and with fewer side effects for the development of drugs for AD. The aim of this study was to perform a technological forecasting alkaloids for the treatment of AD, analyzing the amount of records deposits pat...