10 documents found, page 1 of 1
Cefepime and amoxicillin increase metabolism and enhance caspofungin tolerance ...
Cordeiro, Rossana de Aguiar; Evangelista, Antonio Jose de Jesus; Serpa, Rosana; Andrade, Ana Raquel Colares de; Mendes, Patrícia Bruna LeiteIt is well known that prolonged antibiotic therapy alters the mucosal microbiota composition, increasing the risk of invasive fungal infection (IFI) in immunocompromised patients. The present study investigated the direct effect of b-lactam antibiotics cefepime (CEF) and amoxicillin (AMOX) on biofilm production by Candida albicans ATCC 10231. Antibacterials at the peak plasmatic concentration of each drug were ...
Análise da virulência, sensibilidade antifúngica e mecanismos de resistência a ...
Oliveira, Jonathas Sales deCandida tropicalis, an yeast isolated as comensal from humans and other animals, is a major Candida species associated with serious invasive infections in humans, being also able to cause infection in several animal species. The present study aimed to analyze virulence factors, the susceptibility profile and mechanisms of resistance to azoles in human (n = 24) and veterinary (n = 28) isolates of C. tropicalis, ...
Biofilms of Candida spp. from the ocular conjunctiva of horses with reduced azo...
Brilhante, Raimunda Sâmia Nogueira; Bittencourt, Paula Vago; Castelo-Branco, Debora de Souza Collares; Guedes, Glaucia Morgana de MeloObjectives This study aimed to assess the biofilm-forming ability of Candida spp. from the ocular conjunctiva of horses and to investigate the antifungal susceptibility of these biofilms. Procedures Initially, the biofilm-forming ability of 15 strains was assessed by crystal violet staining, which reveals the fungal biomass adhered to the polystyrene plates, and scanning electron microscopy. Then, the minimum i...
Aeromonas and Plesiomonas species from scarlet ibis ( Eudocimus ruber ) and the...
Castelo-Branco, Débora Souza Collares Maia; Silva, Aline Lobão da; Monteiro, Frederico Ozanan Barros; Guedes, Glaucia Morgana de MeloThe present study aimed at evaluating the role of captive scarlet ibises (Eudocimus ruber) and their environment as reservoirs of Aeromonas spp. and Plesiomonas spp., and analyzing the in vitro antimicrobial susceptibility and virulence of the recovered bacterial isolates. Thus, non-lactose and weak-lactose fermenting, oxidase positive Gram-negative bacilli were recovered from cloacal samples (n = 30) of scarle...
Antiretroviral drugs saquinavir and ritonavir reduce inhibitory concentration v...
Brilhante, Raimunda Sâmia Nogueira; Caetano, Érica Pacheco; Riello, Giovanna Barbosa Riello; Guedes, Glaucia Morgana de MeloRecent studies have shown that some drugs that are not routinely used to treat fungalinfections have antifungal activity, such as protease inhibitor antiretroviral drugs. This studyinvestigated the in vitro susceptibility of Histoplasma capsulatum var. capsulatum to saquinavirand ritonavir, and its combination with the antifungal itraconazole. The susceptibility assaywas performed according to Clinical and Labo...
Evidence of fluconazole-resistant Candida species in tortoises and sea turtles
Brilhante, Raimunda Sâmia Nogueira; Rodrigues, Pedro Henrique de Aragão; Alencar, Lucas Pereira de; Riello, Giovanna Barbosa; Ribeiro, Joyce FontelesThe aim of this study was to evaluate the antifungal susceptibility of Candida spp. recovered from tortoises ( Chelonoidis spp.) and sea turtles ( Chelonia mydas , Caretta caretta , Lepidochelys oli- vacea , Eretmochelys imbricata ). For this purpose, material from the oral cavity and cloaca of 77 animals (60 tortoises and 17 sea turtles) was collected. The collected specimens were seeded on 2 % Sabouraud dextr...
Coccidioidomycosis and histoplasmosis in equines : an overview to support the a...
Brilhante, Raimunda Sâmia Nogueira; Bittencourt, Paula Vago; Lima, Rita Amanda Chaves; Castelo-Branco, Débora; Oliveira, Jonathas Sales deFungal infections of the respiratory tract of horses are not as frequent as those of bacterial and viral origin, often leading to worsening of clinical conditions due to misdiagnosis and incorrect treatment. Coccidioidomycosis and histoplasmosis are systemic mycoses caused by the dimorphic fungi Coccidioides spp. and Histoplasma capsulatum, respectively, which affect humans and a variety of other animals, inclu...
β-Lactam antibiotics and vancomycin inhibit the growth of planktonic and biofil...
Sidrim, José J.C.; Teixeira, Carlos E.C.; Cordeiro, Rossana A.; Brilhante, Raimunda S.N.; Castelo-Branco, Débora S.C.M.; Bandeira, Silviane P.The aim of this study was to evaluate the effects of cefepime, meropenem, piperacillin/tazobactam (TZP) and vancomycin on strains of Candida albicans and Candida tropicalis in planktonic and biofilm forms. Twenty azole-derivative-resistant strains of C. albicans (n = 10) and C. tropicalis (n = 10) were tested. The susceptibility of planktonic Candida spp. to the antibacterial agents was investigated by broth mi...
Simvastatin inhibits planktonic cells and biofilms of Candida and Cryptococcus ...
Brilhante, Raimunda Sâmia Nogueira; Caetano, Erica Pacheco; Oliveira, Jonathas Sales de; Castelo-Branco, Débora de Souza Collares MaiaThe antifungal activity of some statins against different fungal species has been reported. Thus, at the first moment, the in vitro antifungal activity of simvastatin, atorvastatin and pravastatin was tested against Candida spp. and Cryptococcus spp. Then, in a second approach, considering that the best results were obtained for simvastatin, this drug was evaluated in combination with antifungal drugs against p...
Sensibilidade a antifúngicos, atividade exoenzimática e produção de biofilme po...
Oliveira, Jonathas Sales deIn recent years there has been a significant increase in the incidence of fungal infections caused by Candida species. Although C. albicans be considered the principal representing of the genus, other species have been gaining prominence. C. tropicalis, for example, has been associated with serious invasive cadidiases, being the first or second type of non-Candida albicans Candida most commonly isolated in huma...