6 documents found, page 1 of 1
cis-bis(N-benzoyl-N0 ,N0 -dibenzylthioureido) platinum(II) : synthesis, molecul...
Correa, Rodrigo de Souza; Oliveira, Katia Mara de; Pérez, Hiram; Stevens, Ana María Plutín; Cairo, Raúl Ramos; Mocelo, Raúl; Castellano, Eduardo ErnestoIn this paper, the title compound was synthesized from N-benzoyl-N′,N′-dibenzylthiourea ligand and potassium tetrachloroplatinate(II), and its interaction with human (HSA) and bovine (BSA) serum albumin was evaluated. Also, the crystal structure was determined from single-crystal X‐ray diffraction, confirming that the platinum atom is coordinated with two chelated N-benzoyl-N′,N′-dibenzylthiourea ligands in a d...
Nucleobase derivatives as building blocks to borm Ru(II)-based complexes with h...
Carvalho, Diogo Émerson Leite de; Oliveira, Katia Mara de; Bomfim, Larissa Mendes; Soares, Milena Botelho Pereira; Bezerra, Daniel PereiraTwo new Ru(II)-based complexes containing 2-thiouracil derivatives, known as 2-thiouracil (2TU) and 6-methyl-2-thiouracil (6m2TU), were synthesized using cis,trans-[RuCl2(PPh3)2(bipy)] as a precursor. The obtained compounds with a general formula trans-[Ru(2TU)(PPh3)2(bipy)]PF6 (1) and trans-[Ru(6m2TU)(PPh3)2(bipy)]PF6 (2) were characterized by analytical techniques such as NMR, UV–vis, and IR spectroscopies, e...
Novel lawsone-containing ruthenium(II) complexes: Synthesis, characterization a...
De Grandis, Rone Aparecido [UNESP]; Silva dos Santos, Patrick Wellington da; Oliveira, Katia Mara de; Tomazela Machado, Ana Rita; Aissa, Alexandre FerroMade available in DSpace on 2019-10-05T18:18:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); This study describes a series of newly synthesized phosphine/diimine ruthenium complexes containing th...
Complexos de rutênio contendo lapachol e lausona: síntese, caracterização e sua...
Oliveira, Katia Mara deConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The present work focuses on the synthesis and characterization of new ruthenium complexes containing the naphthoquinones lapachol and lawsone, due to the interesting biological properties exhibited by them. Complexes of general formula [Ru(L)(dppb)(N-N)]PF6, trans-[Ru(L)(PPh3)2(N-N)] PF6 and cis-[Ru(PPh3)2(lap)2] where L refers to the ligands...
Ru(II)-based complexes with N-(acyl)-N′,N′-(disubstituted)thiourea ligands : sy...
Correa, Rodrigo de Souza; Oliveira, Katia Mara de; Delolo, Fábio Godoy; Alvarez Hernández, Anislay; Mocelo, Raúl; Plutin, Ana M.Four ruthenium(II)-based complexeswith N-(acyl)-N′,N′-(disubstituted)thiourea derivatives (Th)were obtained. The compounds, with the general formula trans-[Ru(PPh3)2(Th)(bipy)]PF6, interact with bovine serum albumin (BSA) and DNA. BSA-binding constants, which were in the range of 3.3–6.5 × 104 M−1, and the thermodynamic parameters (ΔG, ΔH and ΔS), suggest spontaneous interactions with this protein by electrosta...
Antiparasitic activities of novel ruthenium/lapachol complexes.
Barbosa, Marília Imaculada Frazão; Corrêa, Rodrigo de Souza; Oliveira, Katia Mara de; Rodrigues, Claudia; Ellena, Javier AlcidesUniversidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade de São Paulo. Instituto de Física de São Carlos. São Carlos, ...