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Análise in silico da farmacocinética e farmacodinâmica do composto benzotiazóli...

Mesquita, Felipe Pantoja; Lima, Luina Benevides; Daniel, Julio Paulino; Portilho, Adrhyann Jullyanne de Sousa; Oliveira, Lais Lacerda Brasil de

Gastric adenocarcinoma has high incidence and mortality rates worldwide. The aim of this study was to evaluate the antitumor activity of benzothiazole AFN01 against ACP03 gastric adenocarcinoma cell line. Furthermore, computational prediction of the pharmacokinetics and pharmacodynamics of this molecule and the molecular docking with the relevant pharmacological target found were performed. The MTT assay was pe...

Date: 2020   |   Origin: Oasisbr
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