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Nasal vaccination with attenuated Salmonella expressing VapA: TLR2 activation i...

Cardoso, Silvia Almeida; Oliveira, Aline Ferreira; Ruas, Luciana Pereira; Trevisani, Marcel Montels; Oliveira, Leandro Licursi De; Hanna, Ebert Seixas

Virulent strains of Rhodococcus equi have a large plasmid of 80–90 kb, which encodes several virulence-associated proteins (Vap), including VapA, a lipoprotein highly associated with disease. We have previously demonstrated that oral immunisation with attenuated Salmonella enterica Typhimurium strain expressing the antigen VapA (STM VapA+) induces specific and long-term humoral and cellular immunity against R. ...

Date: 2018   |   Origin: Oasisbr

Antibacterial activity of 7-epiclusianone and Its novel copper metal complex on...

Barros, Mariana de; Perciano, Pedro Griffo; Santos, Marcelo Henrique dos; Oliveira, Leandro Licursi De; Costa, Éderson D’Martin

Mastitis is an inflammation of mammary gland parenchyma that adversely affects bovine health and dairy production worldwide despite significant efforts to eradicate it. The aim of this work was to characterize the antimicrobial activity of 7-epiclusianone (7-epi), a compound extracted from the Rheedia brasiliensis fruit, its complex with copper against Streptococcus spp. isolated from bovine mastitis, and to as...

Date: 2017   |   Origin: Oasisbr

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