5 documents found, page 1 of 1
Immunophenotype of gastric tumors unveils a pleiotropic role of regulatory t ce...
Rocha, S; Basto, AP; Ijsselsteijn, ME; Teles, SP; Azevedo, MM; Gonçalves, G; Gullo, I; Almeida, GM; Maqueda, JJ; Oliveira, MI; Carneiro, F; Barata, JTGastric cancer (GC) patients display increased regulatory T cell (Tregs) numbers in peripheral blood and among tumor-infiltrating lymphocytes. Nevertheless, the role of Tregs in GC progression remains controversial. Here, we sought to explore the impact of Tregs in GCs with distinct histology, and whether Tregs can directly influence tumor cell behavior and GC develop-ment. We performed a comprehensive immunoph...
Phenotypic Analysis of Urothelial Exfoliated Cells in Bladder Cancer via Microf...
Carvalho, S; Abreu, CM; Ferreira, D; Lima, L; Ferreira, JA; Santos, LL; Ribeiro, R; Grenha, V; Martínez-Fernández, M; Duenas, M; Suárez-Cabrera, CBladder cancer is the most common malignancy of the urinary tract, having one of the highest recurrence rates and progression from non-muscle to muscle invasive bladder cancer that commonly leads to metastasis. Cystoscopy and urine cytology are the standard procedures for its detection but have limited clinical sensitivity and specificity. Herein, a microfluidic device, the UriChip, was developed for the enrich...
Atypical Presentation of Langerhans Cell Histiocytocis
Marujo, F; Oliveira, MI; Martins, M; Brito, MJ
Pantoea Species Bacteremia in a Child With Sickle Cell Disease: Looking for a C...
Oliveira, MI; Batalha, S; Gouveia, C; Maia, R; Kjöllerstrom, PPantoea agglomerans has been classically associated with cellulitis or synovitis secondary to penetrating trauma by vegetation. It is an infrequent cause of systemic infections. We describe the case of a 5-year-old girl with sickle cell disease with P. agglomerans bacteremia and review its potential causes.
Fibrinogen scaffolds with immunomodulatory properties promote in vivo bone rege...
Vasconcelos, DM; Gonçalves, RM; Almeida, CR; Pereira, IO; Oliveira, MI; Neves, N; Silva, AM; Ribeiro, AC; Cunha, C; Almeida, AR; Ribeiro, CC; Gil, AMThe hypothesis behind this work is that fibrinogen (Fg), classically considered a pro-inflammatory protein, can promote bone repair/regeneration. Injury and biomaterial implantation naturally lead to an inflammatory response, which should be under control, but not necessarily minimized. Herein, porous scaffolds entirely constituted of Fg (Fg-3D) were implanted in a femoral rat bone defect and investigated at tw...