21 documents found, page 1 of 3
The contribution of genetics to the understanding and management of cardiomyopa...
Cardoso, Isabel; Nunes, Sofia; Brás, Pedro; Viegas, José Miguel; Marques Antunes, Miguel; Ferreira, André; Almeida, Inês; Custódio, InêsGenetics has assumed a pivotal role in clarifying the pathophysiology of cardiomyopathies, facilitating molecular diagnosis, and enabling effective family screening. The advent of next-generation sequencing has revolutionized genetic testing by enabling cost-effective, high-throughput analysis. It is imperative for cardiovascular physicians to mainstream genetic testing into their clinical decision-making. Alth...
A Portuguese expert panel position paper on the management of heart failure wit...
Silva-Cardoso, José; Moreira, Emília; Tavares de Melo, Rachel; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mario; Gavina, Cristina; Moura, BrendaHeart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as we...
The impact of atrial voltage and conduction velocity phenotypes on atrial fibri...
Cunha, Pedro; Laranjo, Sérgio; Monteiro, Sofia; Portugal, Guilherme; Guerra, Cátia; Rocha, António Condeixa; Pereira, Mariana; Ferreira, Rui CruzIntroduction: Low atrial voltage and slow conduction velocity (CV) have been associated with atrial fibrillation (AF); however, their interaction and relative importance as early disease markers remain incompletely understood. We aimed to elucidate the relationship between atrial voltage and CV using high-density electroanatomic (HDE) maps of patients with AF. Methods: HDE maps obtained during sinus rhythm in 5...
Very-early detection of atrial fibrillation after ablation evaluated by a weara...
Marques Antunes, Miguel; Cunha, Pedro; Lacerda Teixeira, Bárbara; Portugal, Guilherme; Valente, Bruno; Lousinha, Ana; Delgado, Ana Sofia; Alves, SandraIntroduction: Atrial fibrillation (AF) ablation represents a safe and effective procedure to restore sinus rhythm. The idea that post-procedural AF episodes - during the blanking period - are not considered treatment failure has been increasingly challenged. The E-Patch, a single-use adhesive electrode, facilitates extended continuous ECG monitoring for 120 h. This pilot study aims to assess the effectiveness o...
Management of life-threatening ventricular arrhythmias: what is going on with a...
Jacinto, Sofia; Reis, João; Oliveira, MarioElectrical storm (ES), characterized by recurrent and frequent episodes of potentially life-threatening ventricular arrhythmias (VA), is a relatively common condition, primarily seen in patients with structural heart disease and implantable cardioverter-defibrillators (ICD). It is a complex severe clinical situation, associated with high mortality and low quality of life. Electrical storm management has evolved...
Epicardial adipose tissue volume assessed by cardiac CT as a predictor of atria...
Teixeira, Bárbara Lacerda; Cunha, Pedro; Jacinto, Ana Sofia; Portugal, Guilherme; Laranjo, Sergio; Valente, Bruno; Lousinha, AnaIntroduction: In patients with atrial fibrillation (AF), up to one third have recurrence after a first catheter ablation (CA). Epicardial adipose tissue (EAT) has been considered to be closely related to AF, with a potential role in its recurrence. We aimed to evaluate the association between the volume of EAT measured by cardiac computed tomography (CT) and AF recurrence after CA. Methods: Consecutive AF patie...
EFAS/EAN survey on the influence of the COVID-19 pandemic on European clinical ...
Fanciulli, Alessandra; Skorić, Magdalena Krbot; Leys, Fabian; Carneiro, Diogo Reis; Campese, Nicole; Calandra-Buonaura, Giovanna; Camaradou, JenniferPurpose: To understand the influence of the coronavirus disease 2019 (COVID-19) pandemic on clinical autonomic education and research in Europe. Methods: We invited 84 European autonomic centers to complete an online survey, recorded the pre-pandemic-to-pandemic percentage of junior participants in the annual congresses of the European Federation of Autonomic Societies (EFAS) and European Academy of Neurology (...
Orthostatic stress and baroreflex sensitivity: a window into autonomic dysfunct...
Ferreira, Mónica; Laranjo, Sergio; Cunha, Pedro; Geraldes, Vera; Oliveira, Mario; Rocha, IsabelThe abnormal neural control of atria has been considered one of the mechanisms of paroxysmal atrial fibrillation (PAF) pathogenesis. The baroreceptor reflex has an important role in cardiovascular regulation and may serve as an index of autonomic function. This study aimed to analyze the baroreceptor reflex's role in heart rate regulation during upright tilt (HUT) in patients with lone PAF. The study included 6...
Non-vitamin K oral anticoagulants assessment in high risk of bleeding patients ...
Silva Cunha, Pedro; Viveiros Monteiro, André; Coutinho Cruz, Madalena; Malveiro, Paula; Reis, João Pedro; Portugal, Guilherme; Dias, AnaAtrial fibrillation (AF) is commonly associated with advanced age and the presence of multiple, concomitant acute and chronic health conditions, placing this population at high risk for serious therapeutic side effects. Nonvitamin K antagonist oral anticoagulants (NOACs) are increasingly used for stroke prevention in patients with atrial fibrillation. The purpose of this study was to investigate the effectivene...
The atrial fibrillation burden during the blanking period is predictive of time...
Cunha, Pedro; Portugal, Guilherme; Laranjo, Sérgio; Alves, Marta; Luísa Papoila, Ana; Valente, Bruno; Sofia Delgado, Ana; Lousinha, AnaObjective: This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid to late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence. Methods: Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring during the second and third months after PVI. The clinical...