3 documents found, page 1 of 1
Immunochemotherapy in american cutaneous leishmaniasis : immunological aspects ...
Toledo, Vicente de Paulo Coelho Peixoto de; Mayrink, Wilson; Gollob, Kenneth John; Oliveira, Milton Adriano Pelli de; Costa, Carlos Alberto daIn this study, we evaluated the immune response of patients suffering from cutaneous leishmaniasis treated with two distinct protocols. One group was treated with conventional chemotherapy using pentavalent antimonium salts and the other with immunochemotherapy where a vaccine against cutaneous leishmaniasis was combined with the antimonium salt. Our results show that, although no differences were observed in t...
Ecto-nucleotidase activities of promastigotes from leishmania (Viannia) brazili...
Leite, Pauline Martins; Gomes, Rodrigo Saar; Figueiredo, Amanda Braga de; Serafim, Tiago Donatelli; Tafuri, Wagner Luiz; Gomes, Carolina CavaliériBackground: Leishmania (Viannia) braziliensis has been associated with a broad range of clinical manifestations ranging from a simple cutaneous ulcer to destructive mucosal lesions. Factors leading to this diversity of clinical presentations are not clear, but parasite factors have lately been recognized as important in determining disease progression. Given the fact that the activity of ecto-nucleotidases corr...
Leishmania spp. parasite isolation through inoculation of patient biopsy macera...
Oliveira, Milton Adriano Pelli de; Pires, Alause da Silva; Bastos, Rosidete Pereira de; Lima, Glória Maria Collet de Araujo; Pinto, Sebastião AlvesIsolation of Leishmania parasite and species identification are important for confirmation and to help define the epidemiology of the leishmaniasis. Mice are often used to isolate pathogens, but the most common mouse strains are resistant to infection with parasites from the Leishmania (Viannia) subgenus. In this study we tested the inoculation of interferon gamma knockout (IFNγ KO) mice with biopsy macera...