4 documents found, page 1 of 1
Phytochemical screening and anticonvulsant property of Ocimum basilicum leaf es...
Oliveira, Juliana S.; Porto, Lívia A.; Estevam, Charles dos Santos; Siqueira, Rosana de Souza; Barreto, Péricles Barreto; Niculau, Edenilson dos SantosOcimum basilicum (Lamiaceae) and other species of the same genus are used as medicines for the treatment of central nervous system (CNS) diseases. In this report, we have investigated the possible CNS depressant and anticonvulsant effects of Ocimum basilicum (access “Maria Bonita”) leaf essential oil (EO) in different experimental models. GC-MS and GC-FID analysis of the essential oil resulted in the identifica...
Epidemiological aspects of dengue in Aracaju, State of Sergipe, Brazil
Alves, José Antonio Barreto; Santos, Jokasta Rodrigues; Mendonça, Emanuelle Nabuco de; Abud, Ana Cristina Freire; Nunes, Mariangela da SilvaINTRODUÇÃO: A dengue permanece como uma doença de elevada significância para a saúde pública e sua incidência tem aumentado nas últimas décadas. Este estudo objetivou caracterizar a incidência epidemiológica da dengue no período de 2001-2010. MÉTODOS: Trata-se de um estudo epidemiológico da dengue no município de Aracaju, Sergipe, no período de 2001 a 2010, cujos dados foram obtidos do Sistema de Informação de ...
Cardiovascular effects of Hyptis fruticosa essential oil in rats
Santos, Márcio Roberto Viana; Carvalho, Adriana Andrade; Medeiros, Isac A.; Alves, Péricles Barreto; Marchioro, Murilo; Antoniolli, Angelo RobertoIn non-anesthetized normotensive rats, Hyptis fruticosa essential oil (HFEO, 5, 10, 20 and 40 mg/kg; i.v.) induced hypotension associated with tachycardia. In intact and isolated rings of rat superior mesenteric artery (control), HFEO (1 – 1000 μ g/ml, n =6, cumulatively) induced concentration-dependent relaxations of tonus induced by 10 μ M phenylephrine (Phe) (pD 2 =2.6±0.27; E max =64±8.3%). In denuded endot...
Ocimum basilicum leaf essential oil and (-)-linalool reduce orofacial nocicepti...
Venâncio, Antônio Medeiros; Marchioro, Murilo; Estevam, Charles dos Santos; Melo, Mônica Santos de; Santana, Marília Trindade deThe present study investigated the antinociceptive effects of Ocimum basilicum L. (Lamiaceae) leaf essential oil (LEO) and (-)-linalool (LIN) in formalin (2%)-, glutamate (25 µM)- and capsaicin (2.5 µg)- induced orofacial nociception models in mice. The involvement of these substances was further evaluated on the neuronal excitability of the hippocampal dentate gyrus. Male mice (n=8/group) were pretreated separ...