Lipid-based nanoparticle systems have been used as vehicles for chemotherapeutic agents in experimental cancer treatments. Those systems have generally been credited with attenuating the severe toxicity of chemotherapeutic agents. This study aimed to investigate the effects of associating paclitaxel (PTX) with a lipid-based nanoparticle system on a nonhuman primate, Cebus apella, documenting the toxicity as mea...
Federal University of Par?. Institute of Biological Sciences. Human Cytogenetics Laboratory. Bel?m, PA, Brazil.; Federal University of Par?. Institute of Biological Sciences. Human Cytogenetics Laboratory. Bel?m, PA, Brazil.; Federal University of Par?. Institute of Biological Sciences. Human Cytogenetics Laboratory. Bel?m, PA, Brazil.; University of S?o Paulo. Heart Institute. Medical School Hospital. S?o Paul...