2 documents found, page 1 of 1
Molecular mechanisms beyond glucose transport in diabetes-related male infertility
Alves, M. G.; Martins, A. D.; Rato, L.; Moreira, P. I.; Socorro, S.; Oliveira, P. F.Diabetes mellitus (DM) is one of the greatest public health threats in modern societies. Although during a few years it was suggested that DM had no significant effect in male reproductive function, this view has been challenged in recent years. The increasing incidence of DM worldwide will inevitably result in a higher prevalence of this pathology in men of reproductive age and subfertility or infertility asso...
Sperm parameters and epididymis function in transgenic rats overexpressing the ...
Correia, S.; Oliveira, P. F.; Guerreiro, P. M.; Lopes, G.; Alves, M. G.; Canario, Adelino; Cavaco, J. E.; Socorro, SilviaSperm undergo maturation acquiring progressive motility and the ability to fertilize oocytes through exposure to the components of the epididymal fluid (EF). Although the establishment of a calcium (Ca-2) gradient along the epididymis has been described, its direct effects on epididymal function remain poorly explored. Regucalcin (RGN) is a Ca-2-binding protein, regulating the activity of Ca-2-channels and Ca-2...