87 documents found, page 1 of 9
Effects of oral supplementation of black-eyed-bean (Vigna unguiculata) in ICR m...
Ferreira, T; Silva-Reis, R; Mendes, BAL; Faustino-Rocha, AI; Carvalho, M; Castro I; Carnide, V; Coutinho, J; Gama, A; Rosa, E; Oliveira, PAGrain legumes are a main source of nutrients in some countries. Black-eyed-bean (BEB) (Vigna unguiculata), a member of theFabaceae family, is a grain legume consumed worldwide due to its high content of bioactive molecules that promote human health. This study aimed to evaluate the effects of 70% BEB flour (BEBF) (w/w) supplementation in ICR healthy mice for 13 weeks. Body and organs weights, as well as food an...
Interplay between western diet and mammary cancer: data from a chemically-induc...
Silva, J; Azevedo, T; Aires, I; Peixoto, F; Neuparth, MJ; Faustino-Rocha, AI; Duarte, JA; Oliveira, PABackground/Aim: This study aimed to investigate the influence of Western diet on mammary cancer in Wistar female rats, focusing on systemic responses and tumor development. Materials and Methods: Twenty-eight Wistar female rats were acclimatized and divided into four experimental groups (n=7 each): Western diet (WD), Western diet with N-methyl-N- nitrosourea (MNU) administration (WD+MNU), standard diet (CTR), a...
Exploring the therapeutical potential of Quercus ilex extract in papillomavirus...
Medeiros-Fonseca, B; Faustino-Rocha, AI; Pires, MJ; Gil da Costa, RM; Oliveira, PABackground and Aim: Papillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. They often exert significant impacts on animal health and livestock production. Scientists have studied natural products for over half a century due to their diverse chemical composition, acknowledging their value in fighting cancer. Acorns (Quercus ilex) are believed to have...
Mammary cancer models: an overview from the past to the future
Silva, J; Oliveira, PA; Duarte, JA; Faustino-Rocha, AIAbstract. Breast cancer research heavily relies on diverse model systems to comprehend disease progression, develop novel diagnostics, and evaluate new therapeutic strategies. This review offers a comprehensive overview of mammary cancer models, covering both ex vivo and in vivo approaches. We delve into established techniques, such as cell culture and explore cutting-edge advancements, like tumor-on-a-chip and...
Effects of ladder-climbing exercise on mammary cancer: data from a chemically i...
Silva, J; Azevedo, T; Faustino-Rocha, AI; Oliveira, PA; Duarte, JABreast cancer is a major health concern for both humans and companion animals, particularly female dogs and cats. This study explores whether resistance training can influence the development of mammary cancer in female rats. The rats were divided into four groups, including those that exercised by climbing a ladder with increasing weight three times a week for 18 weeks. At the end of the study, tumor developme...
Renal biomarkers in companion animals - a review
Pereira, AF; Faustino-Rocha, AI; Oliveira, PA; Coelho, ACSimple Summary: Recent advancements in molecular biology have identified potential biomarkers for diagnosing kidney diseases. They may improve the specificity and sensitiv- ity of diagnoses, allowing early detection and intervention. This review discusses studies on urine and blood biomarkers, highlighting their importance in various clinical settings. Ongoing research is necessary to integrate these biomarkers...
The impact of a Western diet and resistance training in a rat model of mammary ...
Silva, J; Azevedo, T; Faustino-Rocha AI; Duarte, JA; Oliveira, PAThis study aimed to investigate the impact of a Western diet and resistance training on cardiac remodeling in a rat model of chemically induced mammary cancer. Fifty-six female Wistar rats were randomly assigned to one of eight experimental groups, evaluating the impact of Western and standard diets, exercise and sedentarism, and the induction of mammary cancer. Mammary cancer was induced via the intraperitonea...
Chapter: Carcinogenesis.
Jota Baptista, C; Faustino-Rocha, AI; Seixas, F; Oliveira, PACancer is a complex disease with multiple causes. Many intrinsic and extrinsic factors influence the development of cancer. Intrinsic or host factors include age, sex, genetics, immune system, metabolism, and hormones. Extrinsic factors are divided in different groups, as physical (different types of non-ionizing and ionizing radiations); chemical (as some mineral or organic substances); and biological (produce...
Chapter 16: Animal models in phytopharmacology and toxicological testing of pla...
Faustino-Rocha, AI; Medeiros-Fonseca, B; Oliveira, PAChapter 16: Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants
Chemical carcinogens
Oliveira, PA; Faustino-Rocha, AIThis chapter is part of the Handbook of Cancer and Immunology, composed of various volumes addressing several aspects of different cancers, like cancer biology, immunology, interaction with microenvironment, diagnosis, and treatment. This work aimed to provide the readers with an overview of chemical carcinogens, reviewing origin of these chemical agents, their classification, and metabolization, beyond the pro...