Schwannomas are tumors originated from Schwann cells. Normally is located in the head, neck and limbs, but it can occur anywhere in the body where there are myelinated nerves. Renal involvement is rare, with few cases reported in the literature. The preoperative diagnosis is difficult, since it is based only on a specific clinical presentation and limited radiological resources. Although some MRI findings may r...
Purpose: To evaluate the impact of the combination of BRL 37344 and tadalafil (TDF) on the reduction of overactive bladder (OB) symptoms. Methods: Thirty mice were randomized into 5 groups (G) of 6 animals each. L-NAME was used to induce DO. G1: Control; G2: L-NAME; G3: L-NAME + TDF; G4: L-NAME + BRL 37344; G5: L-NAME + TDF + BRL 37344. After 30 days of treatment, the animals were submitted to cystometry to eva...
Orientadores: Carlos Arturo Levi D'Ancona, Edson Antunes; Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas; Resumo: Sintomas do trato urinário inferior (STUI) estão associados com a piora da Qualidade de Vida dos pacientes e geram custos substanciais para a sociedade. Nos últimos anos houve aumento no conhecimento da fisiopatologia e história natural do STUI e obstrução benign...