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Anti-inflammatory effect of the monoterpene myrtenol is dependent on the direct...
Gomes, Bruno S.; S. Neto, Benedito P.; Lopes, Everton M.; Cunha, Francisco V. M.; Araújo, Alyne R.; Wanderley, Carlos W. S.; Wong, Deysi V. T.Myrtenol is a bicyclic monoterpene with anti-in fl ammatory properties. However, the mechanisms involved are partially unknown. Here, we investigated the effect of myrtenol during experimental chronic arthritis and the possible modulating activity of oxidative stress and neutrophil migration. Complete Freund's Adjuvant (CFA)-sensitized rats were treated with vehicle (1 mL/kg, po), myrtenol (12.5, 25 or 50 mg/kg...
Date: 2017
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Origin: Oasisbr