4 documents found, page 1 of 1
Análise de expressão gênica das DNA polimerases com atividade translesão em pac...
Oliveira, Roberta Taiane Germano deAs Síndromes Mielodisplásicas (SMD) são um grupo de doenças clonais das células precursoras hematopoéticas caracterizadas por citopenias, displasias de uma ou mais linhagens celulares, hematopoese ineficaz e risco de progressão para leucemia mieloide aguda. É a doença da medula óssea mais comum em idosos acima de 60 anos, com incidência de até 80 casos/100 mil habitantes/ano. A patogênese da SMD envolve alteraç...
Myelodysplastic syndrome patients present more severe respiratory muscle impair...
Okubo, Bruno Memória; Matos, Anacélia Gomes de; Ribeiro Junior, Howard Lopes; Borges, Daniela de Paula; Oliveira, Roberta Taiane Germano deThe ageing process is associated with gradual decline in respiratory system performance. Anemia is highly prevalent among older adults and usually associated with adverse outcomes. Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic malignancies with increasing incidence with age and characterized by anemia and other cytopenias. The main objectives of this study were to evaluate respiratory...
New polymorphisms of Xeroderma Pigmentosum DNA repair genes in myelodysplastic ...
Santiago, Sabrina Pinheiro; Ribeiro Junior, Howard Lopes; Sousa, Juliana Cordeiro de; Borges, Daniela de Paula; Oliveira, Roberta Taiane Germano deThe association between Xeroderma Pigmentosum DNA repair genes ( XPA rs1800975, XPC rs2228000, XPD rs1799793 and XPF rs1800067) polymorphisms and myelodysplastic syndrome (MDS) have not been reported. To assess the functional role between these polymorphisms and MDS, we evaluated 189 sam- ples stratified in two groups: 95 bone marrow samples from MDS patients and 94 from healthy elderly volunteers used as contr...
Bioinformatics as a pedagogical resource for the biology course in the State Un...
Ribeiro Junior, Howard Lopes; Oliveira, Roberta Taiane Germano de; Ceccatto, Vânia MarilandeThe objective of this study was to evaluate and apply the Bioinformatics theoretical contents and practical for the course students in Biological Sciences Degree Fully enrolled in the disciplines of General Genetics and Molecular Biology, State University of Ceara in 2010. The theoretical approach previously tested (RIBEIRO JUNIOR, 2011) consisted of a presentation of historical concepts, basic and specific to ...