17 documents found, page 1 of 2
Hypoxia and Macrophages Act in Concert Towards a Beneficial Outcome in Colon Ca...
Martins, Flávia; Oliveira, Rosa; Cavadas, Bruno; Pinto, Filipe; Cardoso, Ana Patrícia; Castro, Flávia; Sousa, Bárbara; Pinto, Marta LaranjeiroIn colon cancer, the prognostic value of macrophages is controversial, and it is still unknown how hypoxia modulates macrophage-cancer cell crosstalk. To unravel this, co-cultures of human primary macrophages and colon cancer cells were performed at 20% and 1% O2, followed by characterization of both cellular components. Different colon cancer patient cohorts were analyzed for hypoxia and immune markers, and th...
Fecal microbiota transplantation in the intestinal decolonization of carbapenam...
Silva, João Carlos; Ponte, Ana; Mota, Margarida; Pinho, Rolando; Vieira, Nuno; Oliveira, Rosa; Mota-Carvalho, Nelson; Gomes, Ana Catarina; Afecto, EdgarBackground and aims: fecal microbiota transplantation (FMT) is effective for recurrent Clostridium difficile infection (CDI). Intestinal decolonization of carbapenamase-producing enterobacteriaceae (CPE) can prevent transmission and infection by these agents. The aim of this study was to assess CPE decolonization after FMT. Methods: this was a case-series study that consecutively included all CPE-carriers that ...
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial...
Rigor, Joana; Ferreira, Paula Marques; Murteira, Fábio; Figueiredo, Cristóvão; Vieira, Nuno; Oliveira, Rosa; Couto, Raquel; Mota, MargaridaIntroduction: Outpatient antimicrobial therapy programs have been in place for more than four decades. They provide safe and effective treatment for a selected group of patients while reducing costs. In Europe in general, and in Portugal in particular, these programs are still a relatively new phenomenon. The aim of this study is to describe our center’s two years’ experience with such a program (Antibiotic Cli...
Relationship between the use of new technologies and musculoskeletal symptoms i...
Santos, Paula Clara; Lopes, Sofia; Oliveira, Rosa; Santos, Helena; Mota, Jorge; Mesquita, CristinaChildhood and adolescence are determinants of musculoskeletal development, and the attitudes and habits adopted during these periods can have repercussions in adult life. The increasing use of technologies is becoming more worrying due to the sustained and prolonged postures due to the use of these devices and the consequent impact on musculoskeletal health.
Life quality of students in PBL and traditional teaching models
Silva, Ana; Miranda, Leonor; Oliveira, Alexandra; Salgado, Ana; Magalhães, Andreia; Faias, Joaquim; Oliveira, RosaGetting into Higher Education presents demanding solicitations that may affect academic performance, health and Quality of Life (QL).
Physical activity and low back pain in former athletes
Fleming, Miguel; Miranda, Leonor G.; Oliveira, Rosa; Machado, Isabel; Cunha, Sabrina; Silva, DanielaThe majority of guidelines accentuates the regular physical activity and exercise as a protective factor in chronic pelvic low back pain. Surprisingly, there is some controversy about the possible protective role of physical activity (PA) in low back pain. Objectives: To compare physical activity between former athletes with and without nonspecific chronic pelvic low back pain. To analyze the relationship betwe...
Is antidepressant use associated with breast cancer development? A meta-analysis.
Oliveira, Rosa; Pereira, Andressa; Fernandes, António; Fernandes, RúbenBreast cancer is the most prevalent cancer in women worldwide and there is considerable research proving that depression is an aetiological factor in the development of cancer and a risk factor concerning mortality of breast cancer. Studies in rats also demonstrated a possible development of breast cancer due to antidepressant use. Moreover, even though studies in humans are trifling, the few studies examining ...
Analyzing multiple outcomes: is it really worth the use of multivariate linear ...
Oliveira, Rosa; Teixeira-Pinto, ArmandoIn health related research it is common to have multiple outcomes of interest in a single study. These outcomes are often analysed separately, ignoring the correlation between them. One would expect that a multivariate approach would be a more efficient alternative to individual analyses of each outcome. Surprisingly, this is not always the case. In this article we discuss different settings of linear models an...
HIV voluntary testing among portuguese women attending family planning clinics:...
Cunha Veiga Costa, Eleonora; Oliveira, Rosa; Pereira, Maria Da GraçaThe aim of this article is to analyze the factors associated with HIV testing among 767 sexually active women. Participants were administered several self-report questionnaires that assessed behavioral and psychosocial measures. Overall, 59.8% of the participants reported ever having tested for HIV. Results show that higher levels of education, being pregnant or having been pregnant, concern about AIDS, AIDS kn...
Predictors of consistent condom use among Portuguese women attending family pla...
Cunha Veiga Costa, Eleonora; Oliveira, Rosa; Ferreira, Domingos; Pereira, Maria Da GraçaWomen account for 30% of all AIDS cases reported to the Health Ministry in Portugal and most infections are acquired through unprotected heterosexual sex with infected partners. This study analyzed socio-demographic and psychosocial predictors of consistent condom use and the role of education as a moderator variable among Portuguese women attending family planning clinics. A cross-sectional study using intervi...