2 documents found, page 1 of 1
Cerebral aneurysms associated with human immunodeficiency virus in adults: lite...
Pagiola,Igor Campostrini; Paiva,Aline Lariessy Campos; Aguiar,Guilherme Brasileiro de; Oliveira,Augusto Cesar Penalva de; Conti,Mario Luiz MarquesSUMMARY Introduction: the treatment of human immunodeficiency virus (HIV) infection has been decreasing patient morbidity and mortality by opportunistic infections and, thus, survival has increased. This new reality has been changing the spectrum of diseases affecting such patients. Objective: to discuss the association between HIV and the emergence of aneurysmal brain injuries. Method: it was performed a liter...
Natalizumab treatment for multiple sclerosis: updates and considerations for sa...
Nali,Luiz Henrique da Silva; Moraes,Lenira; Fink,Maria Cristina Domingues; Callegaro,Dagoberto; Romano,Camila Malta; Oliveira,Augusto Cesar Penalva deNatalizumab is currently one of the best options for treatment of patients with Multiple Sclerosis who have failed traditional prior therapies. However, prolonged use, prior immunosuppressive therapy and anti-JCV antibody status have been associated with increased risk of developing progressive multifocal leukoencephalopathy (PML). The evaluation of these conditions has been used to estimate risks of PML in the...