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Modulatory activity of brazilian red propolis on chemically induced dermal carc...

Pinheiro,Kariny Souza; Ribeiro,Danielle Rodrigues; Alves,Angela Valéria Farias; Pereira-Filho,Rose Nely; Oliveira,Clauberto Rodrigues de

PURPOSE:To evaluate modulatory effects of a hydroalcoholic extract of Brazilian red propolis (HERP) on dermal carcinogenesis using a murine model.METHODS: The HERP was used at concentrations of 10, 50 and 100 mg/kg (PROP10, PROP50 and PROP100, respectively) to modulate dermal carcinogenesis induced by the application of 9,10-dimetil-1,2-benzatraceno (DMBA) on the backs of animals.RESULTS:The chemical compounds ...

Date: 2014   |   Origin: Oasisbr

Immunohistochemical profile of stromal constituents and lymphoid cells over the...

Almeida,Bernadeth Moda de; Nascimento,Marismar Fernandes do; Pereira-Filho,Rose Nely; Melo,Genecy Calado de; Santos,José Cleveilton dos

PURPOSE:To assess the evolution profile of the immunohistochemical expression of stromal constituents over the time-course of wound healing in a murine model.METHODS: Surgical wounds were performed in the back of 24 Wistar rats. After three, seven, 14 and 21 days, six rats were euthanized and the wounded histologically processed to assess the immunohistochemical expression of CD3, CD20, CD31, α-SMA and type-I c...

Date: 2014   |   Origin: Oasisbr

Bioassay-guided evaluation of wound healing effect of fatty acids-incorporated ...

Santos,Catharina Grace; Nascimento,Marismar Fernandes do; Oliveira,Clauberto Rodrigues de; Melo,Genecy Calado de; Cardoso,Juliana Cordeiro

PURPOSE: To evaluate the effects of fatty acids-incorporated collagen-based dressing films on wound healing in rodents. METHODS: Therefore, surgical wounds were performed in the back of 80 Wistar rats, and dressed with collgane-based films (COL), and collagen-based films containing fatty acids (AGEF50 and AGEF100). Undressed wounds were regarded as controls (CTR). The animals were euthanized after three, seven,...

Date: 2013   |   Origin: Oasisbr

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