4 documents found, page 1 of 1
Late onset multiple sclerosis: concerns in aging patients
Lotti,Claudia Beatriz de Campos; Oliveira,Acary Souza Bulle; Bichuetti,Denis Bernardi; Castro,Isac de; Oliveira,Enedina Maria LobatoABSTRACT Late onset multiple sclerosis (LOMS) is when the first symptom starts after 50 years of age, representing 4.5% of multiple sclerosis (MS) patients. This study describes the clinical characteristics of patients with LOMS followed at a specialized MS center in São Paulo. Data was obtained from medical records of 742 patients with MS. The LOMS frequency was 4.18%, median age at onset was 54 years and the ...
The profile of patients followed at the Neuroimmunology Clinic at UNIFESP: 20 y...
Bichuetti,Denis Bernardi; Falcão,Alessandra Billi; Boulos,Fernanda de Castro; Morais,Marilia Mamprim de; Lotti,Claudia Beatriz de CamposObjective To describe the clinical activities at the Neuroimmunology Clinic of the Universidade Federal de São Paulo (UNIFESP) from 1994 to 2013. Method The final diagnosis of all patients that attended the center was reviewed and established upon specific guidelines for each disease. The number of total appointments and extra clinical activities (reports and prescriptions) were also analyzed, as are part of ro...
Neuromyelitis optica: brain abnormalities in a Brazilian cohort
Bichuetti,Denis Bernardi; Rivero,René Leandro Magalhães; Oliveira,Daniel May; Souza,Nilton Amorin de; Abdala,Nitamar; Oliveira,Enedina Maria LobatoNeuromyelitis optica (NMO) is a demyelinating disease consisting of relapsing-remitting optic neuritis and myelitis with a more severe course than Multiple Sclerosis. Recently, it has been shown that almost 50% of patients with NMO can have brain magnetic resonance imaging (MRI) abnormalities. We report on six Brazilian patients with NMO, fulfilling the 1999 Wingerchuck criteria for this disease, with abnormal ...
Demyelinating disease in patients with myasthenia gravis
Bichuetti,Denis Bernardi; Barros,Tatiane Martins de; Oliveira,Enedina Maria Lobato; Annes,Marcelo; Gabbai,Alberto AlainMyasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinatin...