9 documents found, page 1 of 1
Translation and cultural validation of the Revised Illness Perception Questionn...
De Nigris Vasconcellos,Fernando; Lima,Felipe Gregório; Oliveira,Enedina Maria Lobato deABSTRACT Background: Multiple sclerosis progression and disability can be rated differently by healthcare professionals. Therefore, how physicians perceive the disease can impact treatment decisions. There are no previous studies on this matter. Objective: To translate and transculturally validate the Revised Illness Perception Questionnaire for Healthcare Professionals (IPQ-R HP), for use in Brazilian Portugue...
Immunosuppressors and immunomodulators in Neurology - Part I: a guide for manag...
Abrantes,Fabiano Ferreira; Moraes,Marianna Pinheiro Moraes de; Albuquerque Filho,José Marcos Vieira de; Alencar,Jéssica Monique DiasABSTRACT For patients with autoimmune diseases, the risks and benefits of immunosuppressive or immunomodulatory treatment are a matter of continual concern. Knowledge of the follow-up routine for each drug is crucial, in order to attain better outcomes and avoid new disease activity or occurrence of adverse effects. To achieve control of autoimmune diseases, immunosuppressive and immunomodulatory drugs act on d...
Employment status of people diagnosed with multiple sclerosis in Brazil
Estrutti,Carolina Martines; Cardoso,Gustavo San Martin Elexpe; Novais,Maykon Anderson Pires de; Oliveira,Enedina Maria Lobato deABSTRACT Objective: To describe the employment status of Brazilians with multiple sclerosis (MS). Methods: Analysis of a cross-sectional online survey including questions on demographic and occupational status at the time of diagnosis and survey completion, and time from the first symptom to diagnosis. Results: Of those who answered the survey, 804 Brazilians with MS were included. Median age of onset and curre...
Multiple sclerosis risk perception and acceptance for Brazilian patients
Bichuetti,Denis Bernardi; Franco,Carolina Azze; Elias,Isaac; Mendonça,Andreia C. R.; Carvalho,Lorraine Fiama Diniz; Diniz,Denise Sisterolli; Tur,CarmenABSTRACT The perception of multiple sclerosis (MS) severity and risk associated with therapies might influence shared decision making in different countries. We investigated the perception of MS severity and factors associated with risk acceptance in Brazil in 96 patients with relapsing-remitting MS using a standardized questionnaire and compared this with two European cohorts. Multiple sclerosis was perceived ...
Positive correlation between functional disability, excessive daytime sleepines...
Braga,Douglas Martins; Prado,Gilmar Fernandes do; Bichueti,Denis Bernardi; Oliveira,Enedina Maria Lobato deABSTRACT Sleep disorders in patients with multiple sclerosis have various causes and interfere with daytime wakefulness. This study assessed the correlation between fatigue, excessive daytime sleepiness and level of disability. Method Retrospective review of medical records from patients with multiple sclerosis to collect data on severity of fatigue, disability, daytime sleepiness, and depression. From 912 medi...
Natalizumab treatment in multiple sclerosis: the experience from two Brazilian ...
Oliveira,Enedina Maria Lobato de; Simm,Renata Faria; Dasic,Gorana; Morais,Marília Mamprim de; Perreira,Samira Luiza dos Apostolos; Callegaro,DagobertoObjective Analyze the demographics, clinical characteristics, efficacy and safety of natalizumab treatment in Brazilian patients with multiple sclerosis (MS) followed up for at least 12 months, in two tertiary MS care centers in São Paulo.Method We evaluated the effect of natalizumab treatment on annualized relapse rate and disability progression in 75 patients with MS treated with natalizumab for at least 12 m...
Why this is not multiple sclerosis: a case based approach
Nicolau,Zaira Fernanda Martinho; Oliveira,Enedina Maria Lobato de; Bichuetti,Denis BernardiObjective To present a case series of patients previously diagnosed as multiple sclerosis (MS) which were later confirmed as an alternative diagnosis, and describe the clinical and paraclinical signs that led to this change. Method Nine patients are described. We reviewed the patient’s clinical chart, magnetic resonance images (MRI) and cerebrospinal fluid. Results There was a mean of three typical symptoms of ...
The real-life experience with cardiovascular complications in the first dose of...
Fragoso,Yara Dadalti; Arruda,Christian Cardoso; Arruda,Walter Oleschko; Brooks,Joseph Bruno Bidin; Damasceno,AlfredoFingolimod is a new and efficient treatment for multiple sclerosis (MS). The drug administration requires special attention to the first dose, since cardiovascular adverse events can be observed during the initial six hours of fingolimod ingestion. The present study consisted of a review of cardiovascular data on 180 patients with MS receiving the first dose of fingolimod. The rate of bradycardia in these patie...
Patients with neuromyelitis optica have a more severe disease than patients wit...
Bichuetti,Denis Bernardi; Oliveira,Enedina Maria Lobato de; Souza,Nilton Amorin de; Tintoré,Mar; Gabbai,Alberto AlainAlthough neuromyelitis optica (NMO) is known to be a more severe disease than relapsing-remitting multiple sclerosis (RRMS), few studies comparing both conditions in a single center have been done.Methods:Comparison of our previously published cohort of 41 NMO patients with 177 RRMS patients followed in the same center, from 1994 to 2007.Results:Mean age of onset was 32.6 for NMO and 30.2 for RRMS (p=0.2062) wi...