2 documents found, page 1 of 1
Modulation of the in vivo inflammatory response by pro-versus anti-inflammatory...
Cunha, C; Teixeira, GQ; Ribeiro-Machado, C; Leite Pereira, C; Ferreira, JR; Molinos, M; Santos, SG; Barbosa, MA; Gonçalves, RMInflammation is central in intervertebral disc (IVD) degeneration/regeneration mechanisms, and its balance is crucial to maintain tissue homeostasis. This work investigates the modulation of local and systemic inflammatory response associated with IVD degeneration/herniation by administration of PRO-versus ANTI-inflammatory treatments. Chitosan/poly-¿-glutamic acid nanocomplexes, known as pro-inflammatory (PRO)...
Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellul...
Ferreira, JR; Teixeira, GQ; Santos, SG; Barbosa, MA; Almeida-Porada, G; Gonçalves, RMMesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells that have been isolated from a variety of tissues, and possess multipotent differentiation capacity, immunomodulatory properties, and are relatively non-immunogenic. Due to this unique set of characteristics, these cells have attracted great interest in the field of regenerative medicine and have been shown to possess pronou...