Funding Information: The results in this publication were produced within the GreenCoat project (project number 03EE5066A), supported by the Federal Ministry of Economic Affairs and Climate Action (BMWK), based on a resolution of the German Parliament. Publisher Copyright: © 2024 The Author(s); A novel characterization technique based on image analysis is presented, intended to complement state-of-the-art refle...
Publisher Copyright: © 2023, The Author(s).; Colorectal cancer (CRC) is the third most common cancer and the second most deathly worldwide. It is a very heterogeneous disease that can develop via distinct pathways where metastasis is the primary cause of death. Therefore, it is crucial to understand the molecular mechanisms underlying metastasis. RNA-sequencing is an essential tool used for studying the transcr...
Funding Information: We would like to thank the excellent contributions from the iMM flow cytometry, rodent, and microscopy facilities. The project that gave rise to these results has received funding from the following sources:”la Caixa” Foundation under the grant agreement LCF/PR/HR19/52160005; European Union’s Horizon 2020 Research and Innovation Programme under grant agreements No 667824; FCT - Portuguese F...
We thank João Neto and remaining Computational Multi-Omics Lab members at UCIBIO for their helpful comments and suggestions. © 2022. The Author(s).; Colorectal cancer (CRC) is a highly diverse disease, where different genomic instability pathways shape genetic clonal diversity and tumor microenvironment. Although intra-tumor heterogeneity has been characterized in primary tumors, its origin and consequences in ...