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Comparison of cytokine RANTES/CCL5 inflammation in apical periodontitis and in ...
Cruz, Joana Vasconcelos e; Notter, Florian; Schick, Fabian; Lechner, JohannBackground: Apical periodontitis (AP) is one of the most common endodontic diseases associated with osteo destructive cytokine production. The literature also reports cytokine studies in fatty degenerative osteonecrotic bone marrow defects (BMDJ/FDOJ) independent of AP. Objective: We compare the RANTES/CCL5 (R/C) chemokine production between AP and BMDJ/FDOJ. For both pathologies, the R/C expression was also co...
Antibacterial effect of ozone on cariogenic bacteria and its potential prejudic...
Santos, Marta; Leandro, Flávia; Barroso, Helena; Delgado, António H. S.; Proença, Luís; Polido, Mário; Cruz, Joana Vasconcelos eOzone is increasingly utilized in dental caries treatment due to its antibacterial properties. In a context of limited studies and no consensus on protocols, this research aims to assess ozone’s antibacterial efficacy on cariogenic bacteria and its potential adverse impact on dentin bond strength. Streptococcus mutans, Streptococcus sobrinus, Lactobacillus casei, and Actinomyces naeslundii suspensions were expo...
Natural antibacterial compounds with potential for incorporation into dental ad...
Sousa, Ana Catarina; Mascarenhas, Paulo; Polido, Mário; Cruz, Joana Vasconcelos eDental adhesives are essential in modern restorative dentistry and are constantly evolving. However, challenges like secondary caries from bacterial infiltration at the adhesive–tooth interface persist. While synthetic antibacterial agents in adhesives show promise, safety concerns have shifted interest toward natural options that are biocompatible, sustainable, and effective. Therefore, this study evaluated wh...
Comparative assessment of different pre-treatment bonding strategies to improve...
Inglês, Magali; Cruz, Joana Vasconcelos e; Azul, Ana Mano; Polido, Mário; Delgado, António H. S.The aim of this study is to compare the adhesive interface formed in dentin, using self-adhesive composites applied with different bonding strategies, by testing the microtensile bond strength (μTBS) and ultramorphology through the use of light microscopy. Permanent, sound human molars were randomly allocated to six experimental groups. The groups included a negative control group, where only etching was perfor...
Improving properties of an experimental universal adhesive by adding a multifun...
Cruz, Joana Vasconcelos e; Delgado, António H. S.; Félix, Samuel; Brito, José; Gonçalves, Luísa; Polido, MárioA vast number of adhesive formulations exist currently. However, available adhesives still have several drawbacks such as increased hydrophilicity, polymerization deficiency, potential cytotoxicity and limited monomer interdiffusion within dentin. To improve material properties, a Bisphenol A-free adhesive containing a novel dendrimer G(2)-isocyanatoethyl methacrylate (G-IEMA) in replacement of Bis-GMA was made...
Dentin bonding and SEM analysis of a new experimental universal adhesive system...
Cruz, Joana Vasconcelos e; Polido, Mário; Brito, José; Gonçalves, Luísa L.Due to their polymerization characteristics, hyper-branched dendrimers have lately shown to be promising candidates for use in dental materials. In this study, a new dental adhesive system was prepared, using a dendrimer derived from 2-isocyanatoethyl methacrylate (G-IEMA), and its adhesive properties were investigated. The exposed dentin was treated with four universal adhesives (UAs): SBU (Scotchbond Universa...
Dentin bonding and SEM analysis of a new experimental universal adhesive system...
Cruz, Joana Vasconcelos e; Polido, Mário; Brito, José; Gonçalves, Luísa L.Due to their polymerization characteristics, hyper-branched dendrimers have lately shown to be promising candidates for use in dental materials. In this study, a new dental adhesive system was prepared, using a dendrimer derived from 2-isocyanatoethyl methacrylate (G-IEMA), and its adhesive properties were investigated. The exposed dentin was treated with four universal adhesives (UAs): SBU (Scotchbond Universa...
A new experimental adhesive system containing G-IEMA – physicochemical properties
Cruz, Joana Vasconcelos e; Brito, José; Polido, Mário; Gonçalves, Luísa L.The ultimate goal of this study was the development of a new Bis-GMA-free dental adhesive system with improved adhesive properties. Instead of Bis-GMA, a dendritic macromer (G-IEMA), derived from 2-isocyanatoethyl methacrylate (IEMA), was used and its physicochemical properties were investigated. G-IEMA was synthesized and subsequently incorporated into an experimental adhesive (AE2) formulated without Bis-GMA....