Background: Breast cancer causes significant psychological and physical burden, with survivors often reporting persistent psychological symptoms, such as anxiety and depression, along with somatic symptoms like fatigue and pain. Psychological factors may protect from the development of long-term distress and help identify patients with greater needs for supervision and/or care. Here we aimed to study the predic...
Background: A diagnosis of cancer, and the resulting treatment process, can be perceived as a life-threatening event, affecting not only patients but also their social network and, more specifically, their relatives. While the ability to cope and adjust to difficult health situations may be challenging, family resilience may optimize a positive adaptation to adversity and contribute to enhance the patient’s qua...
Background/Objective: Screening for depression in patients with cancer can be difficult due to overlap between symptoms of depression and cancer. We assessed validity of the Beck Depression Inventory (BDI-II) in this population. Method: Data was obtained in an outpatient neuropsychiatry unit treating patients with and without cancer. Psychometric properties of the BDI-II Portuguese version were assessed separat...
In past years, clinical trials with psychedelic substances have been conducted to find alternative treatments for hard-to-treat mental health conditions such as treatment-resistant depression, cancer-related depression and anxiety symptoms and post-traumatic stress disorder. Clinical research has advanced under the regulation of national ethical and medication authorities for clinical trials, much as for any st...
There is significant evidence linking a 'reward deficiency syndrome' (RDS), comprising decreased availability of striatal dopamine D2-like receptors (DD2lR) and addiction-like behaviors underlying substance use disorders and obesity. Regarding obesity, a systematic review of the literature with a meta-analysis of such data is lacking. Following a systematic review of the literature, we performed random-effects ...
Introdução: A estimulação cerebral profunda do núcleo subtalâmico (STN-DBS) é um tratamento eficaz para a doença de Parkinson avançada. Contudo, têm sido descritas complicações neuropsiquiátricas importantes, nomeadamente mania. O risco de mania pós-DBS parece ser maior quando são estimuladas áreas ventromediais do núcleo subtalâmico (STN), e é também influenciado pela voltagem e polaridade da estimulação, assi...