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Soluble esterases as biomarkers of neurotoxic compounds in the widespread serpu...

Casu, Valentina; Tardelli, Federica; De Marchi, Lucia; Monni, Gianfranca; Cuccaro, Alessia; Oliva, Matteo; Freitas, Rosa; Pretti, Carlo

The characterization of soluble cholinesterases (ChEs) together with carboxylesterases (CEs) in Ficopomatus enigmaticus as suitable biomarkers of neurotoxicity was the main aim of this study. ChEs of F. enigmaticus were characterized considering enzymatic activity, substrate affinity (acetyl-, butyryl-, propionylthiocholine), kinetic parameters (Km and Vmax) and in vitro response to model inhibitors (eserine he...

Date: 2019   |   Origin: RIA - Repositório Institucional da Universidade de Aveiro
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