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Immune development in HIV-exposed uninfected children born to HIV-infected women

Miyamoto, Maristela; Gouvêa, Aída F.T.B.; Ono, Erika; Succi, Regina Célia M.; Pahwa, Savita; Moraes-Pinto, Maria Isabel de

Immunological and clinical findings suggestive of some immune dysfunction have been reported among HIV-exposed uninfected (HEU) children and adolescents. Whether these defects are persistent or transitory is still unknown. HEU pediatric population at birth, 12 months, 6-12 years were evaluated in comparison to healthy age-matched HIV-unexposed controls. Plasma levels of LPS, sCD14, cytokines, lymphocyte immunop...

Date: 2017   |   Origin: Oasisbr

Desenvolvimento de ELISA indireto simples e de baixo custo para detecção de ant...

Ono, Erika; Lafer, Manuel Mindlin; Weckx, Lily Yin; Granato, Celso; Moraes-Pinto, Maria Isabel de

We have developed a cheaper an simple in house indirect ELISA that uses the live attenuated VZV vaccine as a coating antigen. The alternative ELISA had an agreement of 94% when compared with a commercial VZV ELISA kit. Moreover, our ELISA proved to be more reliable than the kit when assessing true negative samples. By adding a standard serum, we were able to produce results in international units per millilitre...

Date: 2004   |   Origin: Oasisbr

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