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Antimicrobial and cytotoxic activity of fungal mycelial extracts from aquatic e...
Oliveira, Marta Rodrigues de; Santiago, Sarah Raquel Silveira da Silva; Katak, Ricardo de Melo; Camargo, Marlene Rodrigues MarcelinoFungi are a prolific source of biologically active metabolites, including a wide range of clinically important drugs. Therefore, this study aims to evaluate the antimicrobial and cytotoxic activity of secondary metabolites extracted from fungal mycelia isolated from freshwater samples in the state of Amazonas. Mycelial extracts from 12 fungal were used, extracted with MeOH/AcOEt (1:1) according to the criteria ...
Multidrug resistant Pseudomonas aeruginosa survey in a stream receiving effluen...
Magalhães, Mary Joyce Targino Lopes; Pontes, Gemilson Soares; Serra, Paula Takita; Balieiro, Antônio Alcirley da Silva; Castro, Diogo Pereira deBackground: Multi-drug resistant forms of Pseudomonas aeruginosa (MDRPA) are a major source of nosocomial infections and when discharged into streams and rivers from hospital wastewater treatment plants (HWWTP) they are known to be able to persist for extended periods. In the city of Manaus (Western Brazilian Amazon), the effluent of three HWWTPs feed into the urban Mindu stream which crosses the city from its ...
Antimicrobial activity of honeys from two stingless honeybee species and Apis m...
Cruz, Carolinie Batista Nobre da; Pieri, Fabio Alessandro; Carvalho-zilse, Gislene Almeida; Orlandi, Patrícia Puccinelli; Nunes-Silva, Carlos GustavoMéis são descritos possuindo diferentes propriedades, incluindo a antimicrobiana. Muitos estudos têm apresentado essa atividade de méis produzidos por abelhas Apis mellifera, no entanto estudos incluindo atividades de méis de abelhas sem ferrão são escassos. O objetivo deste estudo foi comparar a atividade antimicrobiana de méis de Melipona compressipes, Melipona seminigra e A. mellifera, coletados no Estado do...
Zerumbone from Zingiber zerumbet (L.) smith: A potential prophylactic and thera...
Moreira da Silva, Thiago; Pinheiro, Carlos Danniel; Orlandi, Patrícia Puccinelli; Pinheiro, Carlos Cleomir S.; Pontes, Gemilson SoaresBackground: Essential oil obtained from rhizomes of the Zingiber zerumbet (L.) Smith (popularly known in Brazil as bitter ginger) is mainly constituted by the biomolecule zerumbone, which exhibit untapped antimicrobial potential. The aim of this study was to investigate the antimicrobial activity of the zerumbone from bitter ginger rhizomes against the cariogenic agent Streptococcus mutans. Methods: Firstly, th...