Made available in DSpace on 2022-04-28T18:56:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-01-01; Faculdade de Odontologia UNESP-University Estadual Paulista Departamento de Diagnóstico e Cirurgia; Department of Biointeraction Institute of Health Sciences Federal University, Bahia; Faculdade de Odontologia UNESP-University Estadual Paulista Departamento de Diagnóstico e Cirurgia
Made available in DSpace on 2021-06-25T10:34:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Background: Bioinformatic tools and genome-wide association studies (GWAS) have led to comprehensive identification of single nucleotide polymorphisms (SNPs) associated with periodontitis in diverse populations. Here we aimed to detect and validate the association of seven SNPs as genetic markers of sus...
Made available in DSpace on 2021-06-25T10:48:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Objective: Genome-wide association studies (GWAS) and literature have identified polymorphisms in the KCNJ11, HNF1A, IRS1, TCF7L2, CDKAL1, CDKN2B, RPSAP52, GPR45 HHEX, IL18, and RUNX2 genes associated with type 2 diabetes mellitus (T2DM) and/or periodontitis (P) in diverse populations, and we sought to ...
Made available in DSpace on 2021-06-25T10:52:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Few studies evaluate interrelationships between periodontitis (P) and Type 2 Diabetes Mellitus (T2DM). The aim of this study is to investigate the genetic susceptibility t...
Made available in DSpace on 2020-12-12T02:14:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Objective: To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A, IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes, “classically” related with periodontitis, could be associated with susceptibility to T2DM, and also with both diseases concomitantly. Background: There are common path...
Made available in DSpace on 2020-12-12T02:06:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Type 2 diabetes mellitus (T2DM), dyslipidemia and periodontitis are frequently associated pathologies; however, there are no studies showing the peripheral blood transcript profile of these combined diseases. Here we identified the differentially expressed genes (DEGs) of circulating lymphocytes and mon...
Made available in DSpace on 2018-12-11T17:12:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-06-15; This study aimed to investigate whether the –1026(A>C)(rs2779249) and +2087(A>G)(2297518) polymorphisms in the NOS2gene were associated with chronic periodontitis (CP) and with salivary levels of nitrite (NO2–) and/or nitrate + nitrite (NOx). A group of 113 mixed-race patients were subjected to periodon...