5 documents found, page 1 of 1
The Use of New Therapies for Metastatic Castrate Resistant Prostate Cancer in t...
Botelho, Francisco; Miranda, André; Braga, Isaac; Leão, Ricardo; Teves, Frederico; Dias, Jorge; Rodrigues, Filipe; Oliveira, Jorge; Augusto, IsabelIntroduction:New drugs such as abiraterone (Abi), enzalutamide (Enz), cabazitaxel (Cab) and radium 223 (Rad) were recently approved for metastatic castrate resistant prostate cancer (mCRPC) patients. However, their use in clinical practice is largely unknown, so the objective of this research is to describe their use in mCRPC patients in public hospitals in the north of Portugal. Methods:All mCRPC patients trea...
Avelumab as first-line maintenance treatment in locally advanced or metastatic ...
Mansinho, André; Cruz, Andreia; Marconi, Lorenzo; Pinto, Cidália; Augusto, IsabelThis work provides a summary of guideline recommendations and an expert position on the use of maintenance avelumab therapy based on a review of current international clinical practice guidelines for locally advanced or metastatic urothelial carcinoma (UC). A PubMed literature search was conducted in March 2022 (updated in July 2023) to identify guidelines for locally advanced or metastatic UC. An expert panel ...
Recomendações para a preservação do potencial reprodutivo no doente oncológico
Sousa, Gabriela; Almeida Santos , Ana Teresa; Teixeira, Adriana; Cardoso, Pepe; Melo, Cláudia; Teixeira, Alexandra; Andrade, Joaquim; Silva, CristinaObjective: To provide updated information about the preservation of reproductive potential in adult cancer based on the available evidence. Methods: A review of literature published after 2006 was performed using the Medline and PubMed. The evidence was analyzed by specialists from several medical societies; and reflected upon their onclinical practice. After discussion on several working groups, a series of re...
Recomendações para a preservação do potencial reprodutivo no doente oncológico.
Almeida-Santos, Teresa; Sousa, Gabriela; Teixeira, Adriana; Cardoso, Pepe; Melo, Cláudia; Teixeira, Alexandra; Andrade, Joaquim; Silva, Cristina
Prognostic value of MGMT promoter methylation in glioblastoma patients treated ...
Costa, Bruno Marques; Caeiro, Cláudia; Guimarães, Inês; Martinho, Olga; Jaraquemada, Teresa; Augusto, Isabel; Castro, Lígia; Osório, LígiaGlioblastoma (GBM) is the most common and aggressive primary brain tumor. The identification of novel molecular prognostic markers of GBM has recently been an area of great interest in neuro-oncology. The methylation status of the MGMT gene promoter is currently a promising molecular prognostic marker, but some controversial data have precluded its clinical use. We analyzed MGMT methylation by methylation-speci...