6 documents found, page 1 of 1
Preditores de prognóstico nos Tumores Neuroendócrinos Gástricos: um estudo retr...
Ortigão,Raquel; Afonso,Luís Pedro; Pimentel-Nunes,Pedro; Dinis-Ribeiro,Mário; Libânioa,DiogoResumo Introdução/Objetivo: Os tumores neuroendócrinos gástricos (TNEs-G) têm frequentemente um curso indolente, apesar do seu potencial metastático. O objetivo deste trabalho foi identificar fatores de prognóstico associados à sobrevida global e à metastização nos doentes com TNEs-G e avaliar o impacto da análise seriada de cromogranina A (CgA). Methods: Estudo retrospectivo in-cluindo doentes consecutivos admi...
Anastomotic Leaks following Esophagectomy for Esophageal and Gastroesophageal J...
Ortigão,Raquel; Pereira,Brigitte; Silva,Rui; Pimentel-Nunes,Pedro; Bastos,Pedro; Sousa,Joaquim Abreu de; Faria,Filomena; Dinis-Ribeiro,MárioAbstract Introduction: Anastomotic leakage after esophagectomy is associated with high mortality and impaired quality of life. Aim: The objective of this work was to determine the effec-tiveness of management of esophageal anastomotic leakage (EAL) after esophagectomy for esophageal and gastro-esophageal junction (GEJ) cancer. Methods: Patients submitted to esophagectomy for esophageal and GEJ cancer at a terti...
Endoscopic Resection of Gastrointestinal Neuroendocrine Tumors: Long-Term Outco...
Pimentel-Nunes,Pedro; Ortigão,Raquel; Afonso,Luís Pedro; Bastos,Rui Pedro; Libânio,Diogo; Dinis-Ribeiro,MárioAbstract Introduction: Gastrointestinal neuroendocrine tumors (GI-NETs) are being more frequently diagnosed and treated by endoscopic resection (ER) techniques. However, comparison studies of the different ER techniques or long-term out-comes are rarely reported. Methods: This was a single-center retrospective study analyzing short and long-term outcomes after ER of gastric, duodenum, and rectal GI-NETs. Compar...
Anastomotic Leakages after Surgery for Gastroesophageal Cancer: A Systematic Re...
Azevedo,Isabel; Ortigão,Raquel; Pimentel-Nunes,Pedro; Bastos,Pedro; Silva,Rui; Dinis-Ribeiro,Mário; Libânio,DiogoAbstract Introduction: With the increase of esophageal and gastric cancer, surgery will be more often performed. Anastomotic leakage (AL) is one of the most feared postoperative complications of gastroesophageal surgery. It can be managed by conservative, endoscopic (such as endoscopic vacuum therapy and stenting), or surgical methods, but optimal treatment remains controversial. The aim of our meta-analysis wa...
Improving the Diagnosis and Treatment of Early Gastric Cancer in the West
Libânio,Diogo; Ortigão,Raquel; Pimentel-Nunes,Pedro; Dinis-Ribeiro,MárioAbstract Gastric cancer is the third leading cause of cancer-related death. In Western countries, its lower prevalence and the absence of mass screening programmes contribute to late diagnosis and a slower implementation of minimally invasive treatments. A secondary prevention strategy through endoscopic surveillance of patients at high risk of intestinal-type gastric adenocarcinoma or by screening gastric canc...
Gastrointestinal Microbiome: What We Need to Know in Clinical Practice
Ortigão,Raquel; Pimentel-Nunes,Pedro; Dinis-Ribeiro,Mário; Libânio,DiogoHuman gut microbiota plays an important role in individual health. When the balance between host and gut microbiota is disrupted, changes in microbiota composition and function occur, which is referred as dysbiosis. Environmental factors as diet, proton pump inhibitors, and antibiotics can lead to a permanent dysbiotic disruption. Clarification of these imbalances was made possible by recent advances in genome ...