35 documents found, page 1 of 4
A Comparative Overview of the Role of Human Ribonucleases in Nonsense-Mediated ...
da Costa, Paulo J.; Menezes, Juliane; Guedes, Raquel; Reis, Filipa P.; Teixeira, Alexandre; Saramago, Margarida; Viegas, Sandra C.; Arraiano, Cecília M.Eukaryotic cells possess surveillance mechanisms that detect and degrade defective transcripts. Aberrant transcripts include mRNAs with a premature termination codon (PTC), targeted by the nonsense-mediated decay (NMD) pathway, and mRNAs lacking a termination codon, targeted by the nonstop decay (NSD) pathway. The eukaryotic exosome, a ribonucleolytic complex, plays a crucial role in mRNA processing and turnove...
A Comparative Overview of the Role of Human Ribonucleases in Nonsense-Mediated ...
da Costa, Paulo J.; Menezes, Juliane; Guedes, Raquel; Reis, Filipa P.; Teixeira, Alexandre; Saramago, Margarida; Viegas, Sandra C.; Arraiano, Cecília M.Eukaryotic cells possess surveillance mechanisms that detect and degrade defective transcripts. Aberrant transcripts include mRNAs with a premature termination codon (PTC), targeted by the nonsense-mediated decay (NMD) pathway, and mRNAs lacking a termination codon, targeted by the nonstop decay (NSD) pathway. The eukaryotic exosome, a ribonucleolytic complex, plays a crucial role in mRNA processing and turnove...
Sesimbra
Teixeira, Alexandre; Rio, Ana; Fernandes, Beatriz; Anastácio, Constança; Vyhovska, Daniela; Lopes, Henrique; Cabo, Márcia do; Souza, MatheusRelatório da disciplina de Projeto V, do Mestrado Integrado em Arquitetura da Universidade Autónoma de Lisboa (1º semestre do ano letivo 2022/2023).
Bairro do Viso
Teixeira, Alexandre; Muller, Amanda; Rio, Ana; Fernandes, Beatriz; Neto, Bruna; Mayaputo, Bunga; Anastácio, Constança; Vyhovska, Daniela; Furtado, JoanaLivro da disciplina de Projeto VI do curso de Arqutietura da Universidade Autónoma de Lisboa (ano letivo 2022/23).
Comportamentos suicidários em trabalhadoras de sexo de rua e do interior
Teixeira, Alexandre; Oliveira, Alexandra; Rothes, Inês; Santos, José Carlos Pereira dosEstudo de abordagem mista realizado com trabalhadoras do sexo de rua e interior, com avaliação do risco e fatores predinsponentes.
Cap-independent translation ensures mTOR expression and function upon protein s...
Marques-Ramos, Ana; Romão, Luísa; Candeias, Marco; Menezes, Juliane; Lacerda, Rafaela; Willcocks, M.; Teixeira, Alexandre; Locker, NicolasThe mechanistic/mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates cellular signals from the nutrient and energy status to act, namely, on the protein synthesis machinery. While major advances have emerged regarding the regulators and effects of the mTOR signaling pathway, little is known about the regulation of mTOR gene expression. Here, we show that the human mTOR tra...
Analysis of Pelagia noctiluca proteome Reveals a Red Fluorescent Protein, a Zin...
Frazão, Bárbara; Campos, Alexandre; Osório, Hugo; Thomas, Benjamin; Leandro, Sérgio; Teixeira, Alexandre; Vasconcelos, Vitor; Antunes, AgostinhoPelagia noctiluca is the most venomous jellyfish in the Mediterranean Sea where it forms dense blooms. Although there is several published research on this species, until now none of the works has been focused on a complete protein profile of the all body constituents of this organism. Here, we have performed a detailed proteomics characterization of the major protein components expressed by P. noctiluca. With ...
Analysis of Pelagia noctiluca proteome reveals a red fluorescent protein, a zin...
Frazão, Bárbara; Campos, Alexandre; Osório, Hugo; Thomas, Benjamin; Leandro, Sérgio; Teixeira, Alexandre; Vasconcelos, Vitor; Antunes, AgostinhoPelagia noctiluca is the most venomous jellyfish in the Mediterranean Sea where it forms dense blooms. Although there is several published research on this species, until now none of the works has been focused on a complete protein profile of the all body constituents of this organism. Here, we have performed a detailed proteomics characterization of the major protein components expressed by P. noctiluca. With ...
Ideação suicida em trabalhadoras do sexo. Possiveis contributos para uma estrat...
Teixeira, Alexandre; Oliveira, Alexandra; Santos, José Carlos Pereira dosFoi avaliada a ideação suicida entre trabalhadoras dos exo. a existência de episódios de vitimação física, de vitimação sexual, de consumo de drogas nos últimos 30 dias e da existência de um diagnóstico de saúde mental estão relacionados com u nível superior de ideação suicida.
The human mTOR transcript allows cap-independent translation that insures its e...
Marques-Ramos, Ana; Menezes, Juliane; Candeias, Marco; Willcocks, Mariam; Lacerda, Rafaela; Teixeira, Alexandre; Locker, Nicola; Romão, LuísaThe mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals from the cellular nutrient- and energy-status, acting namely on the protein synthesis machinery. Deregulation of mTOR signaling is implicated in major diseases, such as cancer, mainly due to its role in regulating protein synthesis. Major advances are emerging regarding the regulators and effects of mTOR sign...