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Electrospun polycaprolactone membranes functionalized with nanochitin for enhan...

Costa, Sofia M.; Mattos, Bruno D.; Calhelha, Ricardo C.; Zhu, Ya; Lima, Eurico; Reis, Lucinda; Rojas, Orlando J.; Fangueiro, Raul; Ferreira, Diana P.

The encapsulation of photosensitizers (PSs) in electrospun membranes has emerged as a promising approach in photodynamic therapy (PDT) on tumor sites, overcoming the drawbacks associated with systemic administration. In this work, localized implants for cancer treatment using PDT were developed by incorporating EL-2 squaraine into poly(epsilon-caprolactone) (PCL) electrospun microfibers. The latter were coated ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Electrospun polycaprolactone membranes functionalized with nanochitin for enhan...

Costa, Sofia Maria Soares; Mattos, Bruno D.; Calhelha, Ricardo C.; Zhu, Ya; Lima, Eurico; Reis, Lucinda V.; Rojas, Orlando J.; Fangueiro, Raúl

The encapsulation of photosensitizers (PSs) in electrospun membranes has emerged as a promising approach in photodynamic therapy (PDT) on tumor sites, overcoming the drawbacks associated with systemic administration. In this work, localized implants for cancer treatment using PDT were developed by incorporating EL-2 squaraine into poly(ɛ-caprolactone) (PCL) electrospun microfibers. The latter were coated with c...


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