4 documents found, page 1 of 1
Evaluation of Tissue and Circulating miR-21 as Potential Biomarker of Response ...
Ourô, Susana; Mourato, Cláudia; Ferreira, Marisa P.; Albergaria, Diogo; Cardador, André; Castro, Rui E.; Maio, Rui; Rodrigues, Cecília M. P.Response to chemoradiotherapy (CRT) in patients with locally advanced rectal cancer (RC) is quite variable and it is urgent to find predictive biomarkers of response. We investigated miR-21 as tissue and plasma biomarker of response to CRT in a prospective cohort of RC patients; The expression of miR-21 was analyzed in pre- and post-CRT rectal tissue and plasma in 37 patients with RC. Two groups were defined: P...
Potential of miR-21 to Predict Incomplete Response to Chemoradiotherapy in Rect...
Ourô, Susana; Mourato, Cláudia; Velho, Sónia; Cardador, André; Ferreira, Marisa P.; Albergaria, Diogo; Castro, Rui E.; Maio, RuiBackground: Patients with locally advanced rectal adenocarcinoma (LARC) are treated with neoadjuvant chemoradiotherapy (CRT). However, biomarkers for patient selection are lacking, and the association between miRNA expression and treatment response and oncological outcomes is unclear. Objectives: To investigate miRNAs as predictors of response to neoadjuvant CRT and its association with oncological outcomes. Me...
MORESTIN SYNDROME: BEYOND THORACIC TRAUMA
Watts Soares, Adriana; Veiga Oliveira, Paulo; Lopes, Beatriz; Albergaria, Diogo; Ourô, Susana; Maio, RuiMorestin syndrome (MS) is a rare clinical manifestation consequent to an acute compression trauma to the thorax. In such an event, the sudden elevated pressure that happens to the airway and the rapid and retrograde blood flow results in capillary rupture in the head and neck vessel territory. This case reports a car accident victim that was dragged by a truck down a road with closed thoracic trauma resulting i...
Pancreatic ectopia.
Ourô, Susana; Taré, Filipa; Moniz, LuísPancreatic ectopia (PE) consists in the existence of pancreatic tissue outside its usual location in the normal pancreas. This rare condition, with an uncertain incidence, occurs most often in the stomach, duodenum and jejunum. The ectopic pancreas is usually asymptomatic but it may become clinically significant when it becomes affected with the same kind of complications which affect the normal pancreas - infl...