5 documents found, page 1 of 1
Runs of homozygosity provide a genome landscape picture of inbreeding and genet...
Schiavo, G.; Bovo, S.; Muñoz, M.; Ribani, A.; Alves, E.; Araújo, Pedro Araújo; Bozzi, R.; Candek-Potokar, M.; Charneca, R.; Fernandez, A. I.; Gallo, M.ROHs are long stretches of DNA homozygous at each polymorphic position. The proportion of genome covered by ROHs and their length are indicators of the level and origin of inbreeding. Frequent common ROHs within the same population define ROH islands and indicate hotspots of selection. In this work, we investigated ROHs in a total of 1131 pigs from 20 European local pig breeds and in three cosmopolitan breeds, ...
Describing variability in pig (Sus scrofa) genes coding for receptors and primi...
Bovo, S.; Schiavo, G.; Ribani, A.; Utzeri, V.J.; Taurisano, V.; Ballana, M.; Muñoz, M.; Alves, E.; Araújo, J.P.; Bozzi, R.; Charneca, R.; Di Palma, F.Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral infections. However, at present there is no example that considers pig genetic resources in this context. In this study, we investigated the variability of four genes (ACE2, ANPEP and DPP4 encoding for host rec...
Runs of homozygosity provide a genome landscape picture of inbreeding and genet...
Schiavo, G.; Bovo, S.; Muñoz, M.; Ribani, A.; Alves, E.; Araujo, J.P.; Bozzi, R.; Čandek-Potokar, M.; Charneca, R.; Fernandez, A.I.; Gallo, M.ROHs are long stretches of DNA homozygous at each polymorphic position. The proportion of genome covered by ROHs and their length are indicators of the level and origin of inbreeding. Frequent common ROHs within the same population define ROH islands and indicate hotspots of selection. In this work, we investigated ROHs in a total of 1131 pigs from 20 European local pig breeds and in three cosmopolitan breeds, ...
Whole-genome sequencing of European autochthonous and commercial pig breeds all...
Bovo, S.; Ribani, A.; Muñoz, M.; Alves, E.; Araujo, J.P.; Bozzi, R.; Čandek-Potokar, M.; Charneca, R; Palma, F.D.; Etherington, G.; Fernandez, A.I.Background: Natural and artificial directional selection in cosmopolitan and autochthonous pig breeds and wild boars have shaped their genomes and resulted in a reservoir of animal genetic diversity. Signatures of selection are the result of these selection events that have contributed to the adaptation of breeds to different environments and production systems. In this study, we analysed the genome variability...
Genome-wide detection of copy number variants in European autochthonous and com...
Bovo, S.; Ribani, A.; Muñoz, M.; Alves, E.; Araujo, J.P.; Bozzi, R.; Charneca, R.; Palma, F.D.; Etherington, G.; Fernandez, A.I.; García, F.In this study, we identified copy number variants (CNVs) in 19 European autochthonous pig breeds and in two commercial breeds (Italian Large White and Italian Duroc) that represent important genetic resources for this species. The genome of 725 pigs was sequenced using a breed-specific DNA pooling approach (30–35 animals per pool) obtaining an average depth per pool of 429. This approach maximised CNV discovery...