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Association between self-reported and accelerometer-based estimates of physical...

Domingos, Célia; Santos, Nadine Correia; Pêgo, José M.

Accurate assessment of physical activity (PA) is crucial in interventions promoting it and in studies exploring its association with health status. Currently, there is a wide range of assessment tools available, including subjective and objective measures. This study compared accelerometer-based estimates of PA with self-report PA data in older adults. Additionally, the associations between PA and health outcom...


Useful ultrasonographic parameters to predict difficult laryngoscopy and diffic...

Gomes, Sara Cláudia Santos Hora; Simões, Ana M.; Nunes, Andreia M.; Pereira, Marta V.; Teoh, Wendy H.; Costa, Patrício Soares; Kristensen, Michael S.

The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fmed.2021.671658/full#supplementary-material; Unexpected difficult airway management can cause significant morbidity and mortality in patients admitted for elective procedures. Ultrasonography is a promising tool for perioperative airway assessment, nevertheless it is still unclear which sonographic ...


Validation of a wireless bluetooth photoplethysmography sensor used on the earl...

Correia, Bruno; Dias, Nuno; Costa, Patrício Soares; Pêgo, José M.

Heart rate variability (HRV), using electrocardiography (ECG), has gained popularity as a biomarker of the stress response. Alternatives to HRV monitoring, like photoplethysmography (PPG), are being explored as cheaper and unobtrusive non-invasive technologies. We report a new wireless PPG sensor that was tested in detecting changes in HRV, elicited by a mentally stressful task, and to determine if its signal c...


A systematic review of behavioral, physiological, and neurobiological cognitive...

Ferreira, Sónia; Pêgo, José M.; Morgado, Pedro

Obsessive-compulsive disorder (OCD) is characterized by cognitive regulation deficits. However, the current literature has focused on executive functioning and emotional response impairments in this disorder. Herein, we conducted a systematic review of studies assessing the behavioral, physiological, and neurobiological alterations in cognitive regulation in obsessive-compulsive patients using the PubMed databa...


The efficacy of biofeedback approaches for obsessive-compulsive and related dis...

Ferreira, Sónia; Pêgo, José M.; Morgado, Pedro

Biofeedback is applied to target excessive and/or deficient physiological signals to help patients identifying and self-managing their symptoms. Biofeedback has been employed in psychiatric disorders, including obsessive-compulsive disorder (OCD), mainly by using neural signals - neurofeedback. Recently, OCD has been integrated into the obsessive-compulsive and related disorders (OCD&RD) category (body dysmorph...


MORPhA Scale: behavioral and electroencephalographic validation of a rodent ane...

Esteves, Madalena; Almeida, António M.; Silva, Joana Margarida Gonçalves Mota; Moreira, Pedro Miguel Silva; Carvalho, Emanuel; Pêgo, José M.

Background: Laboratory practice commonly implies rodent anesthesia. Such is instrumental not only for animal welfare, but also for standardized assessment of new anesthetics. New method: We developed and validated a grading system for a temporal follow-up of anesthesia. The Minho Objective Rodent Phenotypical Anesthesia (MORPhA) scale was tested in mice (C57BL/6 J) and rats (WistarHan) anesthetized with ketamin...


Monitoring mental stress through mouse behaviour and decision-making patterns

Gonçalves, Filipe Manuel; Carneiro, Davide Rua; Pêgo, José M.; Novais, Paulo

More and more technological advances offer new paradigmsfor training, allowing novel forms of teaching and learning to be devised.A widely accepted prediction is that computing will move to the back-ground, weaving itself into the fabric of our everyday living spaces andprojecting the human user into the foreground. This forecast turns outto be an opportunity for human-computer interaction as a way to mon-itor ...


Trait determinants of impulsive behavior: a comprehensive analysis of 188 rats

Soares, Ana Rosa; Esteves, Madalena; Moreira, Pedro Miguel Silva; Cunha, Ana Margarida; Guimarães, Marco Rafael Machado; Carvalho, Miguel Murteira

Impulsivity is a naturally occurring behavior that, when accentuated, can be found in a variety of neuropsychiatric disorders. The expression of trait impulsivity has been shown to change with a variety of factors, such as age and sex, but the existing literature does not reflect widespread consensus regarding the influence of modulating effects. We designed the present study to investigate, in a cohort of sign...


EUStress: A human behaviour analysis system for monitoring and assessing stress...

Gonçalves, Filipe Manuel; Carneiro, Davide Rua; Novais, Paulo; Pêgo, José M.

In today’s society, there is a compelling need for innovative approaches for the solution of many pressing problems, such as understanding the fluctuations in the performance of an individual when involved in complex and high-stake tasks. In these cases, individuals are under an increasing demand for performance, driving them to be under constant pressure, and consequently to present variations in their levels ...


A Key Role for Neurotensin in Chronic-Stress-Induced Anxiety-Like Behavior in Rats

Normandeau, Catherine P.; Silva, Ana Paula Ventura; Hawken, Emily R.; Angelis, Staci; Sjaarda, Calvin; Liu, Xudong; Pêgo, José M.; Dumont, É. C.

Accepted Manuscript; Chronic stress is a major cause of anxiety disorders that can be reliably modeled preclinically, providing insight into alternative therapeutic targets for this mental health illness. Neuropeptides have been targeted in the past to no avail possibly due to our lack of understanding of their role in pathological models. In this study we use a rat model of chronic stress-induced anxiety-like ...


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