57 documents found, page 1 of 6
Association between self-reported and accelerometer-based estimates of physical...
Domingos, Célia; Santos, Nadine Correia; Pêgo, José M.Accurate assessment of physical activity (PA) is crucial in interventions promoting it and in studies exploring its association with health status. Currently, there is a wide range of assessment tools available, including subjective and objective measures. This study compared accelerometer-based estimates of PA with self-report PA data in older adults. Additionally, the associations between PA and health outcom...
Useful ultrasonographic parameters to predict difficult laryngoscopy and diffic...
Gomes, Sara Cláudia Santos Hora; Simões, Ana M.; Nunes, Andreia M.; Pereira, Marta V.; Teoh, Wendy H.; Costa, Patrício Soares; Kristensen, Michael S.Unexpected difficult airway management can cause significant morbidity and mortality in patients admitted for elective procedures. Ultrasonography is a promising tool for perioperative airway assessment, nevertheless it is still unclear which sonographic parameters are useful predictors of difficult laryngoscopy and tracheal intubation. To determine the ultrasonographic predictors of a difficult airway that cou...
Validation of a wireless bluetooth photoplethysmography sensor used on the earl...
Correia, Bruno; Dias, Nuno; Costa, Patrício Soares; Pêgo, José M.Heart rate variability (HRV), using electrocardiography (ECG), has gained popularity as a biomarker of the stress response. Alternatives to HRV monitoring, like photoplethysmography (PPG), are being explored as cheaper and unobtrusive non-invasive technologies. We report a new wireless PPG sensor that was tested in detecting changes in HRV, elicited by a mentally stressful task, and to determine if its signal c...
A systematic review of behavioral, physiological, and neurobiological cognitive...
Ferreira, Sónia; Pêgo, José M.; Morgado, PedroObsessive-compulsive disorder (OCD) is characterized by cognitive regulation deficits. However, the current literature has focused on executive functioning and emotional response impairments in this disorder. Herein, we conducted a systematic review of studies assessing the behavioral, physiological, and neurobiological alterations in cognitive regulation in obsessive-compulsive patients using the PubMed databa...
MORPhA Scale: behavioral and electroencephalographic validation of a rodent ane...
Esteves, Madalena; Almeida, António M.; Silva, Joana Margarida Gonçalves Mota; Moreira, Pedro Miguel Silva; Carvalho, Emanuel; Pêgo, José M.Background: Laboratory practice commonly implies rodent anesthesia. Such is instrumental not only for animal welfare, but also for standardized assessment of new anesthetics. New method: We developed and validated a grading system for a temporal follow-up of anesthesia. The Minho Objective Rodent Phenotypical Anesthesia (MORPhA) scale was tested in mice (C57BL/6 J) and rats (WistarHan) anesthetized with ketamin...
The efficacy of biofeedback approaches for obsessive-compulsive and related dis...
Ferreira, Sónia; Pêgo, José M.; Morgado, PedroBiofeedback is applied to target excessive and/or deficient physiological signals to help patients identifying and self-managing their symptoms. Biofeedback has been employed in psychiatric disorders, including obsessive-compulsive disorder (OCD), mainly by using neural signals - neurofeedback. Recently, OCD has been integrated into the obsessive-compulsive and related disorders (OCD&RD) category (body dysmorph...
Trait determinants of impulsive behavior: a comprehensive analysis of 188 rats
Soares, Ana Rosa; Esteves, Madalena; Moreira, Pedro Miguel Silva; Cunha, Ana Margarida; Guimarães, Marco Rafael Machado; Carvalho, Miguel MurteiraImpulsivity is a naturally occurring behavior that, when accentuated, can be found in a variety of neuropsychiatric disorders. The expression of trait impulsivity has been shown to change with a variety of factors, such as age and sex, but the existing literature does not reflect widespread consensus regarding the influence of modulating effects. We designed the present study to investigate, in a cohort of sign...
Inflammatory response and long-term behavioral assessment after neonatal CO2-pn...
Miranda, Alice Augusta Macedo; Roque, Susana; Miranda, Cláudia Sofia Serre; Pêgo, José M.; Correia-Pinto, JorgeBackground: Carbon-dioxide (CO2)-pneumothorax during minimally invasive surgery induces well-known metabolic changes. However, little is known about its impact on the central nervous system.The aim of this work is to evaluate the acute impact of CO2-pneumothorax over central cytokine response and its long-term effect on animal behavior.Methods: This is an experimental study where neonatal Sprague-Dawley rats ar...
X3S: A multi-modal approach to monitor and assess stress through human-computer...
Gonçalves, Filipe Manuel; Carneiro, Davide Rua; Pêgo, José M.; Novais, PauloStress evaluation is nowadays gaining an increasing importance in a time in which inter-individual competition continuously pushes us to be better. Indeed, in the workplace, in the academia or in many other contexts there is increasing pressure for better performance, which pushes us forward but also wears us out. This phenomenon has been studied from many different angles, including psychology, medicine or occ...
A Key Role for Neurotensin in Chronic-Stress-Induced Anxiety-Like Behavior in Rats
Normandeau, Catherine P.; Silva, Ana Paula Ventura; Hawken, Emily R.; Angelis, Staci; Sjaarda, Calvin; Liu, Xudong; Pêgo, José M.; Dumont, É. C.Chronic stress is a major cause of anxiety disorders that can be reliably modeled preclinically, providing insight into alternative therapeutic targets for this mental health illness. Neuropeptides have been targeted in the past to no avail possibly due to our lack of understanding of their role in pathological models. In this study we use a rat model of chronic stress-induced anxiety-like behaviors and hypothe...