Encontrado 1 documento, a visualizar página 1 de 1
Ordenado por
Data
ir para a página:
1
Loss of Hierarchical Imprinting Regulation at the Prader-Willi/Angelman Syndrom...
Pólvora-Brandão, D; Joaquim, M; Godinho, I; Aprile, D; Álvaro, AR; Onofre, I; Raposo, AC; Pereira de Almeida, L; Duarte, ST; da Rocha, STThe human chr15q11-q13 imprinted cluster is linked to several disorders, including Prader-Willi (PWS) and Angelman (AS) syndromes. Recently, disease modeling approaches based on induced pluripotent stem cells (iPSCs) have been used to study these syndromes. A concern regarding the use of these cells for imprinted disease modeling is the numerous imprinting defects found in many iPSCs. Here, by reprogramming ski...
Data: 2018
|
Origem: Repositório do Centro Hospitalar de Lisboa Central, EPE