2 documents found, page 1 of 1
Genetic determinants for prediction of outcome of patients with papillary thyro...
Póvoa, AA; Teixeira, E; Bella-cueto, MR; Batista, R; Pestana, A; Melo, M; Alves, T; Pinto, M; Sobrinho-Simões, M; Maciel, J; Soares, PPapillary thyroid carcinoma (PTC) usually presents an excellent prognosis, but some patients present with aggressive metastatic disease. BRAF, RAS, and TERT promoter (TERTp) genes are altered in PTC, and their impact on patient outcomes remains controversial. We aimed to determine the role of genetic alterations in PTC patient outcomes (recurrent/persistent disease, structural disease, and disease-specific mort...
Clinicopathological features as prognostic predictors of poor outcome in papill...
Póvoa, AA; Teixeira, E; Bella-Cueto, MR; Melo, M; Oliveira, MJ; Sobrinho-Simões, M; Maciel, J; Soares, PPapillary thyroid cancer (PTC) has an indolent nature and usually excellent prognosis. Some PTC clinicopathological features may contribute to the development of aggressive metastatic disease. In this work, we want to evaluate PTC clinicopathological features that are presurgical prognostic predictors of patients’ outcomes and find which indicators are more adequate for tailoring surgical procedures and follow-...