59 documents found, page 1 of 6
Towards Botanical Authentication of Ginkgo Food Supplements: A Holistic Approac...
Grazina, Liliana; Paíga, Paula; Amaral, Joana S.; Costa, Joana; Moreira, Manuela M.; Delerue-Matos, Cristina; Mafra, IsabelGinkgo biloba is one of the most consumed medicinal plants and broadly included as an ingredient in plant food supplements (PFS) and herbal infusions, being potential targets for economically motivated adulteration. This work aimed at comparing the use of DNA and phytochemical markers to authenticate the botanical origin of ginkgo-leaf extracts and PFS. Quantitative real-time PCR was used to detect ginkgo DNA, ...
Seasonal and Spatial Comparison of Polycyclic Aromatic Hydrocarbons Among Decap...
Maia, Maria Luz; Paíga, Paula; Ramalhosa, Maria João; Delerue-Matos, Cristina; Calhau, Conceição; Domingues, ValentinaPolycyclic aromatic hydrocarbons (PAHs) are ubiquitous global pollutants that are lipophilic, bioaccumulative and can be both endocrine disruptors and carcinogens. In this study, we measured 18 PAHs among decapod shrimp samples (Palaemon spp.) collected during the spring and autumn from multiple locations along the Portuguese coastal, including local markets and aquaculture farms. ΣPAH concentrations in samples...
Evaluation of the biological potential of Himanthalia elongata (L.) S.F.Gray an...
Gomes, Inês; Rodrigues, Helena; Rodrigues, Carla; Marques, Marta; Paíga, Paula; Paiva, Alexandre; Simões, Pedro; Cruz Fernandes, VirgíniaNeuroprotection is a need that remains unmet in treating chronic neurodegenerative disorders, despite decades of extensive research. To find new neuroprotective compounds, extracts of Himanthalia elongata (L.) S.F.Gray and of Eisenia bicyclis (Kjellman) Setchell were obtained through subcritical water extraction applying a four-step temperature gradient. The fractions obtained were screened against brain enzyme...
Removal of diclofenac and sulfamethoxazole from aqueous solutions and wastewate...
Soares, Cristina; Correia-Sá, Luísa; Paíga, Paula; Barbosa, Carlos; Remor, Paula Verônica; Freitas, Olga; Moreira, Manuela M.; Nouws, HenriThe three-dimensional (3D) electrochemical treatment process was studied for the removal of two pharmaceuticals, diclofenac (anti-inflammatory) and sulfamethoxazole (antibiotic), in mono and bi-component systems. Adsorption and conventional two-dimensional electrochemical processes were initially studied and then combined to develop the 3D process. The influence of different operating parameters on the removal ...
Evaluation of the Biological Potential of Himanthalia elongata (L.) S.F.Gray an...
Gomes, Inês; Rodrigues, Helena; Rodrigues, Carla; Oliveira, Marta Marques; Paíga, Paula; Paiva, Alexandre; Simões, Pedro; Fernandes, Virgínia CruzNeuroprotection is a need that remains unmet in treating chronic neurodegenerative disorders, despite decades of extensive research. To find new neuroprotective compounds, extracts of Himanthalia elongata (L.) S.F.Gray and of Eisenia bicyclis (Kjellman) Setchell were obtained through subcritical water extraction applying a four-step temperature gradient. The fractions obtained were screened against brain enzyme...
Multi-step subcritical water extracts of fucus vesiculosus l. And codium toment...
Soares, Cristina; Paíga, Paula; Marques, Marta; Neto, Tânia; Carvalho, Ana Paula; Paiva, Alexandre; Simões, Pedro; Costa, Leonor; Bernardo, AnaMental health and active aging are two of the main concerns in the 21st century. To search for new neuroprotective compounds, extracts of Codium tomentosum Stackhouse and Fucus vesiculosus L. were obtained through multi-step (four step) subcritical water extraction using a temperature gradient. The safety assessment of the extracts was performed by screening pharmaceutical compounds and pesticides by UHPLC-MS/M...
Quantification of fluoroquinolones in wastewaters by liquid chromatography-tand...
Maia, Alexandra S.; Paíga, Paula; Delerue-Matos, Cristina; Castro, Paula M. L.; Tiritan, Maria ElizabethAntibiotics are the most consumed therapeutic classes worldwide and are released to the environment in their original form as well as potentially active metabolites and/or degradation products. Consequences of the occurrence of these compounds in the environment are primarily related to bacterial resistance development. This work presents a validated analytical method based on solid phase extraction (SPE) using...
Genotoxicity of gold nanoparticles in the gilthead seabream (Sparus aurata) aft...
Barreto, A.; Luis, L.G.; Pinto, E.; Almeida, A.; Paíga, Paula; H.M.L.M. Santos, Lúcia; Delerue-Matos, Cristina; Trindade, T.; Soares, A.M.V.M.Due to their diverse applications, gold nanoparticles (AuNPs) are expected to increase of in the environment, although few studies are available on their mode of action in aquatic organisms. The genotoxicity of AuNPs, alone or combined with the human pharmaceutical gemfibrozil (GEM), an environmental contaminant frequently detected in aquatic systems, including in marine ecosystems, was examined using gilthead ...
Effects and bioaccumulation of gold nanoparticles in the gilthead seabream (Spa...
Barreto, A.; Luis, L.G.; Pinto, E.; Almeida, A.; Paíga, Paula; Santos, Lúcia H.M.L.M.; Delerue-Matos, Cristina; Trindade, T.; Soares, A.M.V.M.Gold nanoparticles (AuNPs) are found in a wide range of applications and therefore expected to present increasing levels in the environment. There is however limited knowledge concerning the potential toxicity of AuNPs as well as their combined effects with other pollutants. Hence, the present study aimed to investigate the effects of AuNPs alone and combined with the pharmaceutical gemfibrozil (GEM) on differe...
Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC...
Paíga, Paula; Correia, Manuela; Fernandes, Maria João; Silva, Ana Margarida; Martins de Carvalho, Maria Manuela; Vieira, Joana; Jorge, SandraThe removal efficiency of pharmaceuticals in wastewater treatment plants (WWTPs) is variable and some of these compounds pass these plants almost intact and others presenting a removal efficiency close to 100%. Their incomplete removal results in a continuous discharge of pharmaceuticals into the environment. To assess the profile of contamination of influents and effluents over a day, a set of 83 pharmaceutica...