2 documents found, page 1 of 1
Exoproteomic analysis of two MLST clade 2 strains of Clostridioides difficile f...
Pacífico, Dvison de Melo; Costa, Cecília Leite; Moura, Hercules; Barr, John R.; Maia, Guilherme Augusto; Benetti Filho, Vilmar; Moreira, Renato SimõesClostridioides difficile BI/NAP1/ribotype 027 is an epidemic hypervirulent strain found worldwide, including in Latin America. We examined the genomes and exoproteomes of two multilocus sequence type (MLST) clade 2 C. difficile strains considered hypervirulent: ICC‑45 (ribotype SLO231/UK[CE]821), isolated in Brazil, and NAP1/027/ST01 (LIBA5756), isolated during a 2010 outbreak in Costa Rica. C. difficile isolat...
Análise exoproteômica comparativa do sobrenadante de uma cepa de Clostridium di...
Pacífico, Dvison de MeloC. difficile, a Gram-positive, spore-forming anaerobic bacterium, is considered the leading cause of antibiotic-associated diarrhea in hospitalized patients worldwide, causing C. difficile infection (CDI). The main virulence factors of C. difficile are toxins A (TcdA) and B (TcdB), but others, such as surface layer proteins (SLPs) and flagellum, have also been described and related to the observed inflammatory ...